GLP-1 & Metabolic
Metabolic health, appetite regulation, and modern weight management.
112 articles in GLP-1 & Metabolic · page 4 of 10
Semaglutide Weight Loss by Month: What the Trial Data Actually Shows
Semaglutide weight loss by month: the STEP 1 trial's ~15% average at 68 weeks, why the early months are slow, and what a normal trajectory looks like.
Read →Semaglutide and Tirzepatide Titration Schedules: When to Step Up
The full semaglutide dosage chart and tirzepatide dose schedule from the FDA labels, week by week — plus when to step up a dose and when to hold.
Read →GLP-1S Explained: What the Product Code Denotes and the Evidence Behind It
GLP-1S is a vendor product code, not a molecule. What it denotes, the semaglutide science it points at, and why a grey vial is not the FDA drug.
Read →GLP-2T Explained: The Dual-Agonist Product Code and the Evidence
GLP-2T is a vendor code for a tirzepatide-class dual agonist. The drug-class science is strong; the vial in your hand is unverified. The honest split.
Read →GLP-3R Explained: The Triple-Agonist Product Code and the Evidence
GLP-3R is a vendor product code for a retatrutide-class triple agonist. The science is real and phase 2; the grey-market vial is not the drug.
Read →Are GLP-1s Safe Long-Term?
GLP-1 drugs have over a decade of diabetes use and a shorter obesity record. What the multi-year data shows, and what it still cannot answer.
Read →Cagrilintide: The Amylin Analog, Explained
Cagrilintide mimics the pancreatic hormone amylin. Paired with semaglutide as CagriSema it is Novo's next obesity bet — but not yet approved.
Read →GLP-1s and Constipation: Managing the Other GI Effect
Nausea gets the headlines, but constipation is one of the most common GLP-1 side effects. Why it happens, and what helps.
Read →GLP-1s in Pregnancy and Before Conception
GLP-1 drugs are not recommended in pregnancy, and labels call for stopping weeks to months before conceiving. What's known, and what isn't.
Read →"Ozempic Face": Facial Aging and Rapid Fat Loss
Ozempic face is what happens to facial volume during any rapid weight loss, not a pharmacological side effect. The mechanism, and the options.
Read →Ozempic vs Mounjaro: Which and For Whom
Semaglutide and tirzepatide both drive weight loss, but they hit different receptors and rest on different evidence. How to think about the choice.
Read →Retatrutide vs Tirzepatide: Triple vs Dual Agonist
Tirzepatide hits two receptors and is approved. Retatrutide adds a third and posted bigger early numbers — but it is still investigational.
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