Longevity
Biomarkers, healthy aging, preventative health, and lifespan research.
72 articles in Longevity · page 1 of 6
ASCVD 10-Year Cardiovascular Risk, Explained
What your ASCVD risk score means: how the Pooled Cohort Equations estimate 10 year cardiovascular risk, the inputs they use, and how clinicians read the number.
Read →FFMI Explained: Muscle Mass and the Natural Limit
What is FFMI, how the fat free mass index is calculated, and why the ~25 natural FFMI limit is a useful heuristic rather than a hard rule.
Read →The Navy Body Fat Method, Explained
How to measure body fat at home with a tape measure: the Navy body fat method uses circumference math to estimate body fat percentage without calipers or DEXA.
Read →MitoSS-31 vs SS-31: What You're Actually Getting
The product is research-grade SS-31 (elamipretide). The clinical drug is now FDA-approved for one rare disease, and failed most other trials.
Read →L-Carnitine for Fat Metabolism and Recovery: What the Research Shows
L-carnitine shuttles fat into mitochondria, but the human evidence for weight loss and recovery is modest, and a gut-microbiome cardiovascular signal deserves attention.
Read →SLU-PP-332: The 'Exercise Mimetic' Explained
An ERRα agonist that mimics endurance training in mice. There is no human data and it is not approved for people.
Read →CoQ10 and Aging: What the Evidence Shows
CoQ10 has a real, well-defined job in mitochondria and a genuine heart-failure trial behind it. The anti-aging story built on top of that is much thinner.
Read →Creatine for Brain and Cognitive Aging
Creatine isn't just for muscle. It fuels a phosphocreatine energy system in the brain too, and early trials suggest modest cognitive benefits under stress, sleep loss, or low baseline stores.
Read →Fiber and Lifespan: The Underrated Longevity Lever
No supplement stack rivals it: dietary fiber shows one of the most consistent mortality associations in nutrition science, and most people still don't get enough.
Read →Glucosamine and Mortality: The Surprising Signal
Large cohort studies, including UK Biobank, link regular glucosamine use to lower death rates. Here's why that's genuinely interesting and why it isn't proof the supplement extends life.
Read →Is NMN Worth Taking?
NMN reliably raises a NAD+ biomarker in blood. Whether that translates into a longer or healthier life in humans is still an open question.
Read →Rapamycin vs Metformin: The Two Longevity Drugs Compared
Both are prescription drugs repurposed by longevity enthusiasts on the strength of animal data and one unproven human trial. Neither has been shown to extend human life.
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