GLP-1 & Metabolic
Metabolic health, appetite regulation, and modern weight management.
85 articles in GLP-1 & Metabolic · page 5 of 8
Survodutide and the GLP-1/Glucagon Approach
A GLP-1/glucagon dual agonist with phase 2 MASH and obesity data. What's verified, and what isn't.
Read →GLP-1 Shortages: What Drove Them and What's Next
Demand outran supply for years. What caused it, when the FDA called it resolved, and what changed for compounding.
Read →GLP-1s and the Gut Microbiome
A 2025 review found 38 studies but only 9 in humans, with inconsistent diversity results. The thread is real; conclusions aren't.
Read →Generic GLP-1s: When Will Prices Fall?
Generic liraglutide arrived in 2024–2025; semaglutide and tirzepatide are protected far longer. The real timeline.
Read →Protein Intake on a GLP-1: Why It Matters More
DEXA data shows ~40% of GLP-1 weight loss can be lean mass. Why protein and resistance training matter more when appetite drops.
Read →GLP-1s and Cognitive Health: Early Signals
Researchers studied GLP-1s in the brain. The largest Alzheimer's trials came back negative.
Read →Tirzepatide for Heart Failure: The SUMMIT Trial
Tirzepatide cut heart-failure events in obesity-related HFpEF in the SUMMIT trial. What that result does and doesn't show.
Read →GLP-1s and 'Food Noise': The Science of Reduced Cravings
The most striking patient-reported GLP-1 effect may point to the brain's reward circuitry, not just the gut.
Read →Will GLP-1s Work for You? Predicting Response
Response varies widely. What controlled trials say about who loses the most — and the limits of predicting it.
Read →GLP-1s and Exercise: A Better-Together Story
GLP-1 weight loss includes lean mass. Why resistance training changes what kind of weight you lose.
Read →GLP-1s in Type 2 Diabetes vs Obesity: Different Goals
Same drug class, different endpoints, doses, and expectations depending on why it's prescribed.
Read →Rebound Weight After GLP-1s: What Studies Show
STEP 1's extension found people regained two-thirds of lost weight a year after stopping semaglutide. The numbers and what they mean.
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