Longevity
Biomarkers, healthy aging, preventative health, and lifespan research.
72 articles in Longevity · page 2 of 6
The Blueprint Protocol: A Skeptical Look
Bryan Johnson's Blueprint is the most measured self-experiment in longevity. That doesn't mean it proves anything. Here's what's evidence-based and what's still a guess.
Read →Bone Density and Healthy Aging
Why skeletal health quietly determines independence in later decades, and what the trials say helps.
Read →DHEA, Hormones, and Aging
A popular anti-aging hormone, weighed against pooled trial data showing small, sex-specific effects.
Read →Cognitive Reserve and Brain Aging
The buffer that protects thinking with age, and how it's built.
Read →Sarcopenia: Fighting Age-Related Muscle Loss
Sarcopenia has agreed diagnostic cut-points, one intervention with Cochrane-grade evidence — progressive resistance training — and no approved drug.
Read →Reading a Longevity Study: Mice Aren't Men
What the NIA Interventions Testing Program and the animal-to-human translation data show about how much a mouse lifespan result is actually worth.
Read →Frailty and Aging: Prevention Strategies
Frailty is partly preventable and sometimes reversible. What the trial evidence supports.
Read →Why Most Longevity Supplements Disappoint
The structural reasons the supplement aisle rarely matches the press releases.
Read →The Longevity Escape Velocity Debate
A provocative idea, examined against demographic evidence that life-expectancy gains are slowing.
Read →Purpose and Lifespan: The Psychological Evidence
Purpose in life tracks with lower mortality across large cohorts. What that observational finding can and cannot establish.
Read →Social Connection and Longevity
A 148-study meta-analysis tied stronger social ties to a 50% higher odds of survival.
Read →VO2 Max and Lifespan: The Most Underrated Longevity Marker
In 122,007 patients, the least-fit faced ~5x the mortality of the fittest — with low fitness outranking smoking, diabetes, and coronary disease as a risk.
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