| Tirzepatide for the Treatment of Cannabis Use DisorderNCT07265752 | Tirzepatide | Phase 2 | Not yet recruiting | 6 | 2027-03-01 |
| Effects of Tirzepatide on Gut Microbiota and Gastrointestinal Function After Drug Withdrawal in Obese PatientsNCT07847515 | Tirzepatide | — | Not yet recruiting | 80 | 2027-02-01 |
| Patient-centred Intervention With Virtual Support for Obesity and Kidney Transplant AccessNCT07858331 | Semaglutide | Phase 4 | Not yet recruiting | 880 | 2027-01-01 |
| GLP-1/GIP Receptor Agonists in Obesity-Related HFpEF: The GLIDE-HF RegistryNCT07787936 | Liraglutide, Dulaglutide | — | Not yet recruiting | 150 | 2027-01-01 |
| Tirzepatide in Women With Obesity and Endometrial Intra-epithelial Neoplasia or Grade 1 Endometrial CancerNCT07078838 | Tirzepatide | Phase 2 | Not yet recruiting | 40 | 2027-01 |
| A Study of Orforglipron (LY3502970) in Chinese Participants With Obesity or Overweight and Weight-Related Health ProblemsNCT07790861 | Orforglipron | Phase 3 | Not yet recruiting | 192 | 2026-12 |
| SYNCHRONIZE®-START- A Study to Test Whether Survodutide Helps People Living With Overweight or Obesity Who do Not Have Diabetes to Lose WeightNCT07855900 | Semaglutide, Tirzepatide | Phase 3 | Not yet recruiting | 350 | 2026-11-07 |
| Maridebart Cafraglutide Versus Semaglutide in Participants With Type 2 DiabetesNCT07866066 | Semaglutide | Phase 3 | Not yet recruiting | 1300 | 2026-11-02 |
| Comparing Different Medication Regimens to Maintaining Weight Loss Among Adults With Obesity Using GLP-1sNCT07832084 | Semaglutide, Tirzepatide | Phase 4 | Not yet recruiting | 60 | 2026-11-01 |
| Metabolic Surgery for Atrial Fibrillation EliminationNCT07027969 | Liraglutide, Dulaglutide | Phase 4 | Not yet recruiting | 100 | 2026-11-01 |
| Switching to Oral Weight Management Pharmacotherapy to Prevent Weight Regain After GLP-1 Therapy DiscontinuationNCT07729332 | Orforglipron | Phase 4 | Not yet recruiting | 60 | 2026-11-01 |
| Effectiveness and Safety of Tirzepatide Among Participants With Obesity With or Without Type 2 Diabetes Mellitus (T2DM)NCT07099742 | Tirzepatide | — | Not yet recruiting | 364 | 2026-11 |
| GLP-1 Plus Lifestyle for Overall Wellness: Find Your Way ForwardNCT06977438 | Semaglutide | Phase 4 | Not yet recruiting | 1020 | 2026-10-15 |
| A Research Study Investigating How Adults With Overweight or Obesity, With or Without Type 2 Diabetes, Tolerate Switching to a New Treatment (Zenagamtide) From Their Current Tirzepatide MedicationNCT07868354 | Tirzepatide | Phase 1 | Not yet recruiting | 60 | 2026-10-08 |
| FutureShape FamilyNCT07872904 | Semaglutide | Phase 4 | Not yet recruiting | 400 | 2026-10-01 |
| Danish Trial of Weight Loss to Reduce Atrial Fibrillation ProgressionNCT07816744 | Semaglutide | — | Not yet recruiting | 480 | 2026-10-01 |
| A Study to Learn About Switching to a Monthly Study Medicine Called Berobenatide (PF-08653944) to Help Keep Weight Off in People With Overweight or ObesityNCT07845500 | Tirzepatide | Phase 3 | Not yet recruiting | 660 | 2026-10-01 |
| Tirzepatide Versus Positive Airway Pressure for the Treatment of Obstructive Sleep Apnoea: A Randomised Comparative Effectiveness TrialNCT07846865 | Tirzepatide | Phase 2/Phase 3 | Not yet recruiting | 256 | 2026-10-01 |
| Randomized Controlled Trial of Tirzepatide for Methamphetamine Use DisorderNCT07825857 | Tirzepatide | Phase 2 | Not yet recruiting | 228 | 2026-10-01 |
| Comparison of [68Ga]Ga-HBED-CC-PEG6-Exendin-4 and [68Ga]Ga-HBED-CC-Exendin-4 PET/CT for Insulinoma LocalizationNCT07808879 | Exenatide | — | Recruiting | 20 | 2026-10-01 |
| PATHS-T2D: A Recall-by-Genotype Study of Physiologic and Pharmacologic ResponsesNCT07739537 | Orforglipron | Phase 4 | Not yet recruiting | 100 | 2026-10-01 |
| Semaglutide 2.4 mg Once Weekly for Recurrent Weight Gain After Metabolic and Bariatric Surgery (RESURGE)NCT07859150 | Semaglutide | Phase 4 | Not yet recruiting | 104 | 2026-10 |
| Immediate Versus Criterion-triggered Semaglutide for Suboptimal Clinical Response One Year After Primary Metabolic and Bariatric SurgeryNCT07859189 | Semaglutide | Phase 4 | Not yet recruiting | 100 | 2026-10 |
| Tapered Versus Abrupt Discontinuation of Semaglutide After Treatment of Recurrent Weight Gain or Suboptimal Response Following Metabolic and Bariatric SurgeryNCT07859176 | Semaglutide | Phase 4 | Not yet recruiting | 100 | 2026-10 |
| Semaglutide Before Primary Metabolic and Bariatric Surgery in Patients With BMI 60 kg/m² or HigherNCT07859137 | Semaglutide | Phase 4 | Not yet recruiting | 100 | 2026-10 |
| Semaglutide Given Before and After Conversion of Sleeve Gastrectomy to Roux-en-Y Gastric Bypass for Recurrent Weight GainNCT07859163 | Semaglutide | Phase 4 | Not yet recruiting | 100 | 2026-10 |
| Phase II Study of Switching From Dulaglutide to PG-102(MG12) in Type 2 Diabetes MellitusNCT07677891 | Dulaglutide | Phase 2 | Not yet recruiting | 60 | 2026-10 |
| A Research Study Investigating How Adults With Overweight or Obesity, With or Without Type 2 Diabetes, Tolerate Switching to a New Treatment (Zenagamtide) From Their Current Semaglutide MedicationNCT07855133 | Semaglutide | Phase 1 | Not yet recruiting | 60 | 2026-09-30 |
| Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS)NCT07817875 | Tirzepatide | Phase 3 | Recruiting | 150 | 2026-09-25 |
| NAION in Non-Diabetic Obese Patients Using GLP-1 Receptor Agonists: A Real-World StudyNCT07846956 | Tirzepatide | — | Not yet recruiting | 28 | 2026-09-21 |
| Tirzepatide in Thrombectomy-Treated Acute Ischemic Stroke: A Randomized TrialNCT07734792 | Tirzepatide | Phase 2/Phase 3 | Not yet recruiting | 726 | 2026-09-20 |
| A Study of BGM0504 in Early T2DM With ObesityNCT07743983 | Semaglutide | Phase 3 | Recruiting | 372 | 2026-09-17 |
| Weight-loss Drug for Fertility-Sparing Treatment of Atypical Hyperplasia and Low-grade Cancer of the EndometriumNCT06073184 | Semaglutide | Phase 2 | Recruiting | 71 | 2026-09-17 |
| Research Study on How People With Type 2 Diabetes Tolerate Switching From Semaglutide to CagrisemaNCT07817251 | Cagrilintide | Phase 3 | Recruiting | 210 | 2026-09-16 |
| Tirzepatide for Treatment of CCCANCT07734870 | Tirzepatide | Phase 2 | Recruiting | 20 | 2026-09-15 |
| A Study of Tirzepatide (LY3298176) in Participants With Type 1 Diabetes Mellitus and Overweight or ObesityNCT07803744 | Tirzepatide | Phase 1 | Recruiting | 18 | 2026-09-11 |
| IBI3042 Study in Healthy Participants and Overweight or Obese ParticipantsNCT07793019 | Orforglipron | Phase 1 | Recruiting | 104 | 2026-09-07 |
| A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 DiabetesNCT07668336 | Dulaglutide, Orforglipron | Phase 3 | Not yet recruiting | 170 | 2026-09 |
| MODERN-Dental: Pediatric Obesity, Cardiometabolic Risks, And Periodontal DiseaseNCT07478653 | Semaglutide | — | Recruiting | 50 | 2026-08-31 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASC35 Injection in Participants With Obesity or OverweightNCT07842640 | Tirzepatide | Phase 1 | Recruiting | 84 | 2026-08-27 |
| A Research Study to Compare Two Different Versions of Injectable CagriSema in People With Type 2 DiabetesNCT07357740 | Cagrilintide | Phase 2 | Withdrawn | 0 | 2026-08-27 |
| A Neuropsychobiological Approach to Optimize Patient Selection for GLP-1-based Pharmacotherapy for Weight Management Across the Binge Eating SpectrumNCT07870538 | Semaglutide | Phase 4 | Recruiting | 96 | 2026-08-26 |
| A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 ObesityNCT07794579 | Orforglipron | Phase 3 | Recruiting | 2001 | 2026-08-26 |
| A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 DiabetesNCT07282613 | Cagrilintide | Phase 3 | Recruiting | 80 | 2026-08-04 |
| A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body WeightNCT07745504 | Cagrilintide | Phase 3 | Recruiting | 285 | 2026-08-04 |
| Imaging in Semaglutide StudyNCT07695454 | Semaglutide | — | Recruiting | 10 | 2026-07-30 |
| A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes Who Observe Ramadan FastingNCT07613307 | Orforglipron | Phase 3 | Recruiting | 130 | 2026-07-15 |
| Body Composition Changes After Initiation of GLP-1 Receptor Agonists in Adults With Obesity or Type 2 DiabetesNCT07835360 | Tirzepatide | — | Recruiting | 200 | 2026-07-10 |
| Trial of Innovative Fat-loss Focused Approaches in Patients With Class I Obesity: a Comparative StudyNCT07866183 | Tirzepatide | — | Recruiting | 120 | 2026-06-29 |
| A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 DiabetesNCT07668388 | Semaglutide | Phase 2 | Recruiting | 300 | 2026-06-22 |
| A Research Study to Compare Different Versions of Injectable CagriSema and Placebo in People With Excess Body WeightNCT07357766 | Cagrilintide | Phase 3 | Withdrawn | 0 | 2026-06-22 |
| Determination of Resistance Training Status for Patients on Glucagon-Like Peptide-1 Receptor AgonistsNCT07702461 | Liraglutide, Dulaglutide, Exenatide | — | Recruiting | 300 | 2026-06-12 |
| TP04HN106 in the Treatment of Patients With Amyotrophic Lateral SclerosisNCT06726577 | Liraglutide | Phase 1/Phase 2 | Recruiting | 60 | 2026-06-04 |
| GLP-1 Receptor Agonist Use and Sarcopenia in Obese Individuals Without DiabetesNCT07858864 | Semaglutide, Tirzepatide | — | Recruiting | 42 | 2026-05-30 |
| Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse EventsNCT07607587 | Cagrilintide | Phase 1 | Recruiting | 114 | 2026-05-29 |
| A Phase 2a Study of ALN-PNP With and Without a GLP1R Agonist in Adult Patients With Homozygous PNPLA3-Related MASLDNCT07527910 | Tirzepatide | Phase 2 | Recruiting | 204 | 2026-05-22 |
| A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose WeightNCT07564414 | Cagrilintide | Phase 3 | Recruiting | 2500 | 2026-05-21 |
| Tirzepatide s Dopaminergic Effects in Alcohol Use Disorders (AUD)NCT07559500 | Tirzepatide | Phase 1 | Recruiting | 176 | 2026-05-20 |
| A Research Study to Compare Blood Levels of Two Different Versions of Cagrilintide in Adults With Excess Body WeightNCT07605052 | Cagrilintide | Phase 1 | Completed | 50 | 2026-05-20 |
| A Research Study to Compare Blood Levels of Cagrilintide After Multiple Doses of Different Versions of Cagrilintide in Adults With Overweight or ObesityNCT07597018 | Cagrilintide | Phase 1 | Recruiting | 234 | 2026-05-18 |
| RWS of of Liraglutide Alone and in Combination With Orlistat for Weight Loss in Overweight/Obese Patients.NCT07301437 | Liraglutide | Phase 4 | Not yet recruiting | 120 | 2026-05-01 |
| Efficacy and Safety of Triple Therapy With Dulaglutide, SGLT2 Inhibitors, and Finerenone in Chinese Adults With Type 2 Diabetes and Chronic Kidney DiseaseNCT07537088 | Dulaglutide | Phase 4 | Not yet recruiting | 468 | 2026-05 |
| A Research Study Looking Into How Cagrilintide Influences Food Intake and Appetite in People With Overweight or ObesityNCT07557953 | Cagrilintide | Phase 1 | Recruiting | 120 | 2026-04-30 |
| Targeting Agonists of Glucagon-like Peptide-1 Receptor for Multiple SclerosisNCT07497399 | Exenatide | Phase 2 | Recruiting | 120 | 2026-04-28 |
| Tirzepatide in Obesity-Driven Endometrial CancerNCT07065552 | Tirzepatide | EARLY_Phase 1 | Recruiting | 20 | 2026-04-27 |
| Understanding the Effect of CagriSema, Cagrilintide, and Semaglutide on Muscle Health (Role of Amylin Signature in Muscle Health)NCT07527195 | Cagrilintide | Phase 1 | Recruiting | 100 | 2026-04-10 |
| Rapid and Simultaneous Initiation of Four Guideline-Directed CKD Therapies (RAPID-CKD)NCT07547878 | Semaglutide | Phase 4 | Enrolling by invitation | 64 | 2026-04-08 |
| The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With ObesityNCT07218445 | Tirzepatide | Phase 4 | Recruiting | 40 | 2026-04-08 |
| A Study to Estimate Early Clinical Efficacy Signals of GLP-1 Agonist Administration in Conjunction With Levonorgestrel Intrauterine Device in Obese Patients With Endometrioid Intraepithelial NeoplasiaNCT07107334 | Liraglutide, Orforglipron | Phase 2 | Recruiting | 20 | 2026-04-07 |
| A Study to Evaluate ALN-2232 in Participants With ObesityNCT07463846 | Tirzepatide | Phase 1/Phase 2 | Recruiting | 156 | 2026-03-02 |
| Visceral Adipose Tissue and Liver Changes Associated With Semaglutide in CKDNCT07187830 | Semaglutide | — | Recruiting | 52 | 2026-02-23 |
| Real-world Canadian Retrospective Study Evaluating Longitudinal Semaglutide Use on Cardio-Kidney-Metabolic OutcomesNCT07424430 | Semaglutide | — | Completed | 3392 | 2026-02-20 |
| Effect of LY3437943 Versus Placebo in Participants Who Have Obesity or Are OverweightNCT07467447 | Retatrutide | Phase 2 | Recruiting | 300 | 2026-02-15 |
| The Evira Study: Additional Support During Obesity TreatmentNCT06836284 | Liraglutide | — | Recruiting | 40 | 2026-02-13 |
| A Study Looking at How Weekly Injections of Two Hormones - GIP and Amylin - Affect Stomach-related Side Effects in People Who Are Overweight or ObeseNCT07411560 | Cagrilintide | Phase 1 | Recruiting | 100 | 2026-02-09 |
| Emulation of the REWIND Cardiovascular Outcomes Trial in Healthcare Claims Data.NCT07417631 | Dulaglutide | — | Completed | 300000 | 2026-02-03 |
| INcreTin-based thERapies for Cardiovascular Event PrevenTion in Patients With and Without ASCVD (INTERCEPT-ASCVD)NCT07417618 | Dulaglutide | — | Completed | 60000 | 2026-01-27 |
| A Study of Retatrutide (LY3437943) in Participants Without Type 2 Diabetes Who Have Obesity or OverweightNCT07357415 | Retatrutide | Phase 3 | Active not recruiting | 600 | 2026-01-24 |
| Injectable Semaglutide vs Dulaglutide in Individuals at Cardiovascular RiskNCT07619495 | Dulaglutide | — | Completed | 120000 | 2026-01-20 |
| A Single-Center, Open-Label, Single Ascending Dose Study of Exenatide Circular RNA-Lipid Nanoparticle Injection (CR059) in Chinese Subjects With Type 2 Diabetes MellitusNCT07347080 | Exenatide | EARLY_Phase 1 | Recruiting | 9 | 2026-01-20 |
| A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body WeightNCT07253285 | Cagrilintide | Phase 3 | Recruiting | 460 | 2026-01-08 |
| Estimating the Impact of Obesity Medications on Clinical and Economic OutcomesNCT07640139 | Liraglutide | — | Enrolling by invitation | 125000 | 2026-01-01 |
| Efficacy and Safety of Ribupatide Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have DiabetesNCT07284979 | Semaglutide | Phase 3 | Active not recruiting | 1270 | 2025-12-30 |
| A Study to Evaluate the Effect of Fasting Duration and Dulaglutide (LY2189265) Withholding on Gastric Retention in Participants With Type 2 Diabetes MellitusNCT07313813 | Dulaglutide | Phase 1 | Completed | 20 | 2025-12-29 |
| Role of GLP1 RA Dulaglutide on Severe Intracranial AtherosclerosisNCT07282041 | Dulaglutide | Phase 2/Phase 3 | Recruiting | 130 | 2025-12-17 |
| Impact of Discontinuing GLP-1 Receptor Agonists for Two Weeks Prior to Upper Endoscopy on the Risk of Gastric RetentionNCT07276763 | Dulaglutide | — | Not yet recruiting | 16509 | 2025-12-10 |
| A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)NCT07241390 | Orforglipron | Phase 3 | Recruiting | 7140 | 2025-12-01 |
| ELITE: Deep Profiling and Algorithmic Polytherapy to Map Individual Response in Healthy AgingNCT07871799 | Semaglutide | Phase 2 | Completed | 31 | 2025-11-17 |
| A Study of Retatrutide (LY3437943) in Participants With Obesity or OverweightNCT07232719 | Retatrutide | Phase 3 | Active not recruiting | 250 | 2025-11-17 |
| Weekly GLP-1 Receptor Agonists in Obese Individuals Without DiabetesNCT07834398 | Dulaglutide | Phase 3 | Completed | 150 | 2025-11-14 |
| Examination of How the Duration of Fasting and Temporary Stopping of GLP-1 Medications Affect the Amount of Food Left in the Stomach in People Using Liraglutide (Injected), Semaglutide (Taken by Mouth) or Semaglutide (Injected)NCT07225816 | Liraglutide | Phase 1 | Recruiting | 71 | 2025-11-07 |
| Weight Loss in People Living With Overweight or Obesity and Type 2 Diabetes Following Treatment With CagrilintideNCT07220759 | Cagrilintide | Phase 3 | Active not recruiting | 330 | 2025-11-05 |
| Weight Loss in People Living With Overweight or Obesity Following Treatment With CagrilintideNCT07220642 | Cagrilintide | Phase 3 | Active not recruiting | 300 | 2025-11-05 |
| Efficacy and Safety of Orforglipron in Participants With Peripheral Artery DiseaseNCT07223593 | Orforglipron | Phase 3 | Recruiting | 1205 | 2025-10-31 |
| Comparative Study of Different Weekly GLP-1 Receptor Agonists Among Diabetic and Non-Diabetic Patients: Clinical TrialNCT07820111 | Dulaglutide | Phase 3 | Completed | 159 | 2025-10-18 |
| A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)NCT07165028 | Tirzepatide, Retatrutide | Phase 3 | Recruiting | 4500 | 2025-10-15 |
| A Phase 3 Study of HS-20094 in Patients With T2DMNCT07156539 | Dulaglutide | Phase 3 | Not yet recruiting | 546 | 2025-09-30 |
| A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or OverweightNCT07202884 | Orforglipron | Phase 3 | Recruiting | 1000 | 2025-09-30 |
| A Study to See How Metabolism is Influenced by Weight Loss Due to Intervention With Cagrilintide and Semaglutide Compared to DietNCT07184086 | Cagrilintide | Phase 1 | Active not recruiting | 80 | 2025-09-26 |
| Using Secondary Data to Evaluate Sex-based Heterogeneity of GLP-1 Agonists and SGLT2 Inhibitors on Cardiovascular-Kidney-Metabolic Health (CKMH) Outcomes in Real-world Settings (DASH-CKMH)NCT07188545 | Dulaglutide, Exenatide | — | Active not recruiting | 23280000 | 2025-09-15 |
| A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the KneeNCT07153471 | Orforglipron | Phase 3 | Active not recruiting | 800 | 2025-09-15 |
| Role of Glucagon-like Peptide-1 Receptor Agonists in Menstrual Irregularities in Adolescent Females With Type 1 Diabetes MellitusNCT07319286 | Dulaglutide | Phase 1/Phase 2 | Enrolling by invitation | 50 | 2025-08-04 |
| Bone Metabolism in 12-21 Year Olds Undergoing Glucagon Like Peptide (GLP)-1 Receptor Agonist TherapyNCT06903923 | Liraglutide | Phase 2 | Recruiting | 120 | 2025-07-31 |
| Probiotics in Obese Patients Treated With SemaglutideNCT07847593 | Semaglutide | — | Completed | 102 | 2025-07-09 |
| GLP-1s to Enhance Lasting Optimal WeightNCT06861439 | Tirzepatide | Phase 4 | Active not recruiting | 40 | 2025-07-07 |
| A Study of BGM0504 in Participants With Type 2 Diabetes in IndonesiaNCT07064486 | Semaglutide | Phase 3 | Active not recruiting | 152 | 2025-07-04 |
| Pre-Surgical Tirzepatide-Assisted Weight Loss in Overweight and Obese Men With Intermediate Risk Prostate Cancer: A Pilot Feasibility StudyNCT06759701 | Tirzepatide | EARLY_Phase 1 | Recruiting | 30 | 2025-07-02 |
| Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b StudyNCT06937086 | Tirzepatide | Phase 3 | Recruiting | 350 | 2025-06-26 |
| Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or OverweightNCT06937099 | Tirzepatide | Phase 3 | Recruiting | 290 | 2025-06-26 |
| A Trial to Investigate the Safety and Efficacy of Intra-articular 4P004 Injection in Subjects With Knee Synovitis and OsteoarthritisNCT07225829 | Liraglutide | Phase 2 | Active not recruiting | 129 | 2025-06-17 |
| The Role of the Amylin Analogue Cagrilintide in Bone MetabolismNCT07010432 | Cagrilintide | Phase 1 | Recruiting | 144 | 2025-06-12 |
| A Study to Investigate the Response of Participants With Type 2 Diabetes Mellitus on Once-Weekly Retatrutide to HypoglycemiaNCT06982846 | Retatrutide | Phase 1 | Completed | 80 | 2025-06-06 |
| A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-termNCT07011667 | Cagrilintide | Phase 3 | Active not recruiting | 609 | 2025-06-03 |
| Semaglutide for Helping Opioid RecoveryNCT06639464 | Semaglutide | Phase 2 | Recruiting | 46 | 2025-06-02 |
| A Study to Evaluate the Effect of Retatrutide on Insulin Secretion and Insulin Sensitivity in Adult Participants With Type 2 Diabetes MellitusNCT06982859 | Semaglutide, Retatrutide | Phase 1 | Active not recruiting | 95 | 2025-06-02 |
| A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back PainNCT07035093 | Retatrutide | Phase 3 | Active not recruiting | 586 | 2025-05-29 |
| Impact of Pharmacogenetic-Guided Treatment on Type 2 Diabetes.NCT06851962 | Dulaglutide | Phase 4 | Completed | 92 | 2025-05-26 |
| Tirzepatide vs Liraglutide in BoneNCT07094568 | Liraglutide | — | Recruiting | 72 | 2025-05-23 |
| A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight With and Without Type 2 DiabetesNCT06993792 | Orforglipron | Phase 3 | Active not recruiting | 1400 | 2025-05-15 |
| A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and at Least One Weight-Related ComorbidityNCT06972459 | Orforglipron | Phase 3 | Active not recruiting | 800 | 2025-05-15 |
| A Study of HDM1005 in Participants With T2DM Not Controlled With Diet/Exercise or MetforminNCT07109700 | Dulaglutide | Phase 2 | Recruiting | 216 | 2025-04-30 |
| A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1NCT06948435 | Orforglipron | Phase 3 | Active not recruiting | 487 | 2025-04-30 |
| A Master Protocol for Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight: (ATTAIN-Hypertension Screening)NCT06948422 | Orforglipron | Phase 3 | Active not recruiting | 974 | 2025-04-30 |
| A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL2NCT06952530 | Orforglipron | Phase 3 | Active not recruiting | 487 | 2025-04-30 |
| Glycemic and Weight Loss Effects of GLP-1R Agonist Therapy in Subjects With Spinal Cord Injury and Type 2 DiabetesNCT06706284 | Semaglutide | Phase 4 | Recruiting | 50 | 2025-04-11 |
| A Study of BGM0504 in Participants With ObesityNCT06911203 | Tirzepatide | Phase 2 | Completed | 96 | 2025-04-09 |
| A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or TirzepatideNCT06897475 | Semaglutide, Tirzepatide | Phase 2 | Recruiting | 200 | 2025-03-28 |
| Response to Semaglutide in Non-diabetic Obese Patients With Varying Degrees of Insulin ResistanceNCT06856291 | Semaglutide | — | Completed | 40 | 2025-03-15 |
| A Study of Retatrutide (LY3437943) in the Maintenance of Weight Reduction in Individuals With ObesityNCT06859268 | Retatrutide | Phase 3 | Active not recruiting | 643 | 2025-03-05 |
| Sequential Therapy Anti-obesitY Medication With Muscle Preservation for Weight Loss and MaintEnance: A PragmAtic Randomized CoNtrolled Trial (STAY-LEAN Trial)NCT06854614 | Tirzepatide | Phase 4 | Active not recruiting | 150 | 2025-03-01 |
| A Research Study to Look Into the Long-term Effect on Weight Loss of CagriSema in People With ObesityNCT06780449 | Cagrilintide | Phase 3 | Active not recruiting | 400 | 2025-02-10 |
| Tirzepatide for Obesity and Meth Use DisorderNCT06745128 | Tirzepatide | Phase 2 | Completed | 35 | 2025-02-03 |
| To Investigate the Effect of Retatrutide (LY3437943) on Metoprolol Pharmacokinetics in Healthy ParticipantsNCT06808802 | Retatrutide | Phase 1 | Completed | 30 | 2025-02-03 |
| Study of Patients Being Treated With Anti-obesity MedicationNCT06790160 | Semaglutide, Tirzepatide | — | Active not recruiting | 100 | 2025-01-31 |
| A Research Study to Investigate the Effects of CagriSema Compared to Placebo in People With Type 2 Diabetes and Painful Diabetic Peripheral NeuropathyNCT06797869 | Cagrilintide | Phase 2 | Completed | 142 | 2025-01-29 |
| A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)NCT06739122 | Dulaglutide | Phase 3 | Recruiting | 55 | 2025-01-10 |
| Semaglutide in Women With Polycystic Ovary Syndrome and ObesityNCT06896981 | Semaglutide | Phase 2/Phase 3 | Completed | 31 | 2025-01-01 |
| Beta Cell Function in Type 2 Diabetes: Differential Effects of SGLT2 Inhibitors and GLIP-Receptor AgonistsNCT07325435 | Liraglutide, Dulaglutide | Phase 4 | Active not recruiting | 60 | 2024-12-21 |
| Assessment of Safety, Tolerability and Drug Levels of Exenatide ImplantNCT05670379 | Exenatide | Phase 1 | Completed | 24 | 2024-12-20 |
| A First-In-Human Study of ARO-INHBE in Adults With Obesity With and Without Type 2 Diabetes MellitusNCT06700538 | Tirzepatide | Phase 1/Phase 2 | Recruiting | 180 | 2024-12-04 |
| A Study on How NNC0174-1213 Works in People With Overweight or Obesity.NCT06719011 | Cagrilintide | Phase 1 | Completed | 178 | 2024-12-03 |
| A Research Study to Compare Blood Levels of Cagrilintide and Semaglutide After Single Doses of Different Versions of Injectable CagriSema in Adults With Overweight or ObesityNCT06716307 | Cagrilintide | Phase 1 | Completed | 18 | 2024-12-02 |
| Glucagon-Like Peptide 1 Receptor Agonist in Diabetes Mellitus Management in Children and Adolescents With Transfusion-Dependent ThalassemiaNCT07370922 | Dulaglutide | Phase 2 | Completed | 80 | 2024-11-22 |
| Subcutaneous Tirzepatide Once-weekly in Patients With Obesity and Knee Osteoarthritis (STOP KNEE-OA)NCT06191848 | Tirzepatide | Phase 4 | Active not recruiting | 352 | 2024-11-19 |
| A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)NCT06672549 | Orforglipron | Phase 3 | Recruiting | 125 | 2024-11-18 |
| A Study of Orforglipron (LY3502970) in Adolescent Participants With Obesity, or Overweight With Related ComorbiditiesNCT06672939 | Orforglipron | Phase 3 | Recruiting | 150 | 2024-11-18 |
| A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or BothNCT06534411 | Cagrilintide | Phase 3 | Completed | 1023 | 2024-11-05 |
| A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have ObesityNCT06662383 | Retatrutide | Phase 3 | Active not recruiting | 800 | 2024-11-01 |
| Comparative Study of Tirzepatide Versus Dulaglutide (SURPASS CVOT) or Semaglutide on Major Cardiovascular Events in Participants With Type 2 DiabetesNCT06779929 | Dulaglutide | — | Completed | 70000 | 2024-11-01 |
| A Master Protocol for Orforglipron in Participants With Obstructive Sleep Apnea and Obesity or OverweightNCT06649045 | Orforglipron | Phase 3 | Completed | 712 | 2024-10-22 |
| Food (Poly)Phenol Metabotypes and Beta-cell Mass and Function.NCT06888167 | Exenatide | — | Recruiting | 40 | 2024-10-14 |
| Residual Gastric Content After Holding of Glucagon-like Peptide-1 Receptor Agonists Before Elective SurgeryNCT06500143 | Dulaglutide | — | Completed | 94 | 2024-10-09 |
| Comparative Effectiveness of Tirzepatide and Semaglutide in Individuals at Cardiovascular RiskNCT07096063 | Dulaglutide | — | Completed | 887132 | 2024-10-01 |
| Prediction of the SURPASS-CVOT Cardiovascular Outcome Trial in Healthcare Claims DataNCT07088718 | Dulaglutide | — | Completed | 44671 | 2024-10-01 |
| A Pan-European Post-Authorisation Safety Study: Risk of Pancreatic Cancer Among Type 2 Diabetes Patients Who Initiated Exenatide as Compared With Those Who Initiated Other Non-Glucagon-Like Peptide 1 Receptor Agonists Based Glucose Lowering DrugsNCT05663515 | Exenatide | — | Recruiting | 24000 | 2024-09-30 |
| A Study to Investigate Weight Management With LY3841136 and Tirzepatide (LY3298176), Alone or in Combination, in Adult Participants With Obesity or Overweight With Type 2 DiabetesNCT06603571 | Tirzepatide | Phase 2 | Completed | 367 | 2024-09-20 |
| A Study of Orforglipron for the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-MAINTAIN)NCT06584916 | Orforglipron | Phase 3 | Completed | 376 | 2024-09-13 |
| The Chronic Kidney Disease Adaptive Platform Trial Investigating Various Agents for Therapeutic EffectNCT06058585 | Semaglutide | Phase 3 | Recruiting | 2000 | 2024-09-04 |
| Real-World Evaluation of Omarigliptin for Type 2 Diabetes Meliitus in BangladeshNCT06449235 | Exenatide | Phase 4 | Unknown | 938 | 2024-09 |
| Effect of Liraglutide in Obese Women With Polycystic Ovary SyndromeNCT05965908 | Liraglutide | Phase 3 | Completed | 183 | 2024-08-01 |
| Exenatide For Reducing the Reinforcing Effects of CocaineNCT06252623 | Exenatide | Phase 1 | Withdrawn | 0 | 2024-08-01 |
| Holding vs. Continuing Incretin-based Therapies Before Upper EndoscopyNCT06533527 | Dulaglutide | Phase 4 | Completed | 69 | 2024-07-31 |
| A Phase 3 Study to Evaluate the Efficacy of JY09 Compared With Dulaglutide in Combination Therapy Diabetes Mellitus Type 2 Patients With MetforminNCT06257966 | Dulaglutide, Exenatide | Phase 3 | Active not recruiting | 600 | 2024-07-17 |
| Fibrosis Lessens After Metabolic SurgeryNCT06374875 | Liraglutide | Phase 4 | Recruiting | 120 | 2024-07-11 |
| A Phase 3 Study to Evaluate the Efficacy of JY09 Compared With Placebo in T2DM PatientsNCT06254014 | Exenatide | Phase 3 | Active not recruiting | 270 | 2024-07-10 |
| Risk Factors Affect Weight Loss Outcomes After Treatment.NCT06482411 | Liraglutide | — | Completed | 3602 | 2024-06-27 |
| A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose WeightNCT06388187 | Cagrilintide | Phase 3 | Completed | 300 | 2024-06-24 |
| A Study to Compare Tablets and Capsules of Orforglipron (LY3502970) in Healthy Participants Who Are Obese or OverweightNCT06440980 | Orforglipron | Phase 1 | Completed | 533 | 2024-06-24 |
| The Effect of Oral Semaglutide on Bone Turnover in Patients With T2D: a Randomized Placebo-controlled Clinical TrialNCT06050577 | Semaglutide | Phase 2 | Active not recruiting | 64 | 2024-06-07 |
| A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)NCT06439277 | Tirzepatide | Phase 3 | Recruiting | 300 | 2024-06-03 |
| Diabetes Islet Preservation Immune TreatmentNCT02586831 | Exenatide | Phase 1/Phase 2 | Withdrawn | 0 | 2024-06-01 |
| Effects of NNC0194-0499, Cagrilintide, and Semaglutide Alone or in Combinations on Liver Damage and Alcohol Use in People With Alcohol-related Liver DiseaseNCT06409130 | Cagrilintide | Phase 2 | Completed | 270 | 2024-05-20 |
| Investigating How CagriSema, Semaglutide and Cagrilintide Regulate Insulin Effects in the Body of People With Type 2 DiabetesNCT06403761 | Cagrilintide | Phase 1 | Completed | 158 | 2024-05-06 |
| A Drug-Drug Interaction (DDI) Study of Orforglipron With Carbamazepine in Healthy ParticipantsNCT06370728 | Orforglipron | Phase 1 | Completed | 30 | 2024-05-06 |
| The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)NCT06383390 | Retatrutide | Phase 3 | Active not recruiting | 10000 | 2024-04-30 |
| Effect of Retatrutide Compared With Placebo in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone (TRANSCEND-T2D-1)NCT06354660 | Retatrutide | Phase 3 | Completed | 537 | 2024-04-10 |
| Study to Evaluate the Safety and Effectiveness of Saxenda® for Weight Management in Routine Clinical Practice in Taiwan.NCT06283641 | Liraglutide | — | Completed | 300 | 2024-04-08 |
| A Study of TG103 Injection Combined With Metformin in Treatment of Type 2 Diabetes MellitusNCT06235086 | Dulaglutide | Phase 3 | Completed | 632 | 2024-04-08 |
| A Research Study to See if Kidney Damage in People With Chronic Kidney Disease and Type 2 Diabetes Living With Overweight or Obesity Can be Reduced by CagriSema Compared to Semaglutide, Cagrilintide and PlaceboNCT06131372 | Cagrilintide | Phase 2 | Completed | 626 | 2024-04-01 |
| Use of Liraglutide in Children Aged 6 to 12 Years With Severe ObesityNCT07590219 | Liraglutide | Phase 4 | Active not recruiting | 30 | 2024-03-30 |
| A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Once-daily Basal Insulin With or Without MetforminNCT06323161 | Cagrilintide | Phase 3 | Completed | 274 | 2024-03-26 |
| A Study to Measure Calorie Consumption and Usage in Participants With Obesity Using LY3437943NCT06313528 | Retatrutide | Phase 1 | Completed | 85 | 2024-03-20 |
| GLP-1 Receptor Agonist for Reduction of Myocardial Injury After Non-cardiac SurgeryNCT06324461 | Dulaglutide | Phase 4 | Recruiting | 372 | 2024-03-20 |
| A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Diet and ExerciseNCT06323174 | Cagrilintide | Phase 3 | Completed | 189 | 2024-03-19 |
| Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)NCT06297603 | Retatrutide | Phase 3 | Active not recruiting | 320 | 2024-03-15 |
| A Study on How CagriSema Affects Levels of Atorvastatin and Warfarin in the Blood of Participants With Excess Body WeightNCT06289504 | Cagrilintide | Phase 1 | Completed | 34 | 2024-02-27 |
| A Research Study to Look at How CagriSema Influences Food Intake, Appetite and Emptying of the Stomach in People With Excess Body WeightNCT06207877 | Cagrilintide | Phase 1 | Completed | 62 | 2024-02-23 |
| Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2)NCT06260722 | Retatrutide | Phase 3 | Active not recruiting | 1250 | 2024-02-21 |
| A Study of How CagriSema Works on Appetite in People With Excess Body WeightNCT06267092 | Cagrilintide | Phase 1 | Completed | 164 | 2024-02-15 |
| A Study of HS-20094 in Patients With T2DMNCT06901648 | Dulaglutide | Phase 2 | Completed | 275 | 2024-02-06 |
| Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory IssuesNCT06171152 | Liraglutide | EARLY_Phase 1 | Suspended | 30 | 2024-01-26 |
| A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 InhibitorNCT06221969 | Cagrilintide | Phase 3 | Completed | 1024 | 2024-01-16 |
| Association of Gene Polymorphism With Susceptibility to T2DM and the Therapeutic Responses to Exenatide in Chinese Patients With T2DMNCT06256419 | Exenatide | — | Recruiting | 300 | 2024-01-01 |
| Pharmacological Treatment - An Overview of Its Role in Managing Childhood ObesityNCT07304141 | Liraglutide | — | Completed | 128 | 2023-12-20 |
| A Research Study to See How Well CagriSema Compared to Tirzepatide Helps People With Obesity Lose WeightNCT06131437 | Cagrilintide | Phase 3 | Completed | 809 | 2023-11-27 |
| A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or OverweightNCT06143956 | Tirzepatide | Phase 2 | Recruiting | 1481 | 2023-11-17 |
| A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes and Inadequate Glycemic Control With Insulin Glargine, With or Without Metformin and/or SGLT-2 InhibitorNCT06109311 | Orforglipron | Phase 3 | Completed | 546 | 2023-11-10 |
| Influence of JY09 on Pharmacokinetics of Metformin , Rosuvastatin , and Digoxin and the QT Interval Study in Overweight Chinese SubjectsNCT06247748 | Exenatide | Phase 1 | Completed | 28 | 2023-10-19 |
| A Phase I Study of LY3502970 in Healthy ParticipantsNCT06085482 | Orforglipron | Phase 1 | Completed | 10 | 2023-10-19 |
| Therapeutic Strategies for Microvascular Dysfunction in Type 1 DiabetesNCT05478707 | Dulaglutide | Phase 2 | Recruiting | 47 | 2023-10-05 |
| A Long-term Safety Study of Orforglipron (LY3502970) in Participants With Type 2 DiabetesNCT06010004 | Orforglipron | Phase 3 | Completed | 401 | 2023-09-28 |
| A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 InhibitorNCT06065540 | Cagrilintide | Phase 3 | Completed | 2734 | 2023-09-27 |
| A Study of Orforglipron (LY3502970) Compared With Semaglutide in Participants With Type 2 Diabetes Inadequately Controlled With MetforminNCT06045221 | Orforglipron | Phase 3 | Completed | 1698 | 2023-09-22 |
| A Study of LY3502970 in Chinese Participants With Obesity or Are Overweight With Weight-related ComorbiditiesNCT06023095 | Orforglipron | Phase 1 | Completed | 24 | 2023-09-21 |
| Clinical, Morphometric and Biochemical Effects on Adiposopathy Associated With the Use of GLP-1RA in CKDNCT07309094 | Dulaglutide, Exenatide | — | Recruiting | 250 | 2023-09-15 |
| A Study of LY3437943 in Postmenopausal Female Participants Who Are Overweight or ObeseNCT06039826 | Retatrutide | Phase 1 | Completed | 46 | 2023-09-12 |
| Research on Timing of Liraglutide Therapy in Patients With Obesity After Metabolic SurgeryNCT07374445 | Liraglutide | Phase 4 | Completed | 100 | 2023-09-01 |
| A Research Study Looking at Similarity Between LY3437943 Versions for Different Injection DevicesNCT06003465 | Retatrutide | Phase 1 | Completed | 57 | 2023-08-29 |
| A Research Study to See How Well CagriSema Helps People in China With Excess Body Weight Lose WeightNCT05996848 | Cagrilintide | Phase 3 | Completed | 300 | 2023-08-15 |
| A Study of Orforglipron (LY3502970) in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise AloneNCT05971940 | Orforglipron | Phase 3 | Completed | 559 | 2023-08-09 |
| A Study of Retatrutide (LY3437943) Once Weekly in Participants Who Have Obesity or Overweight and Osteoarthritis of the KneeNCT05931367 | Retatrutide | Phase 3 | Completed | 445 | 2023-08-01 |
| A Study of Once-Daily Oral Orforglipron (LY3502970) in Japanese Adult Participants With Obesity DiseaseNCT05931380 | Orforglipron | Phase 3 | Completed | 238 | 2023-07-31 |
| A Study of Retatrutide (LY3437943) on Renal Function in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 DiabetesNCT05936151 | Retatrutide | Phase 2 | Completed | 146 | 2023-07-20 |
| A Study of LY3437943 in Healthy Participants With a High Body Mass IndexNCT05959096 | Retatrutide | Phase 1 | Completed | 85 | 2023-07-18 |
| A Study of LY3437943 in Participants With Impaired and Normal Liver FunctionNCT05916560 | Retatrutide | Phase 1 | Completed | 43 | 2023-07-13 |
| A Phase 1, Parallel, Single-Dose, Open-Label, Single-Period Study of LY3502970 in Participants With Normal Renal Function and Participants With Renal Impairment.NCT05936138 | Orforglipron | Phase 1 | Completed | 24 | 2023-07-13 |
| A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or OverweightNCT05929079 | Retatrutide | Phase 3 | Completed | 1152 | 2023-07-11 |
| A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or OverweightNCT05929066 | Retatrutide | Phase 3 | Completed | 2335 | 2023-07-10 |
| A Research Study on How Well Semaglutide Helps Children and Teenagers With Excess Body Weight Lose WeightNCT05726227 | Semaglutide | Phase 3 | Active not recruiting | 212 | 2023-07-07 |
| Preoperative Weight Loss for Open Abdominal Wall ReconstructionNCT05925959 | Liraglutide | — | Recruiting | 258 | 2023-06-19 |
| A Study of LY3502970 in Participants With Impaired and Normal Liver FunctionNCT05882032 | Orforglipron | Phase 1 | Completed | 29 | 2023-06-13 |
| A Study of Orforglipron in Adult Participants With Obesity or Overweight and Type 2 DiabetesNCT05872620 | Orforglipron | Phase 3 | Completed | 1613 | 2023-06-05 |
| A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight With Weight-Related ComorbiditiesNCT05869903 | Orforglipron | Phase 3 | Active not recruiting | 3127 | 2023-06-05 |
| A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular DiseaseNCT05882045 | Retatrutide | Phase 3 | Completed | 1946 | 2023-05-30 |
| Effects of GH and Lirglutide on AgRPNCT05681299 | Liraglutide | Phase 4 | Recruiting | 40 | 2023-05-01 |
| A Multiple Dose Study of LY3502970 in Healthy Overweight and Obese ParticipantsNCT05841238 | Orforglipron | Phase 1 | Completed | 52 | 2023-04-26 |
| Exenatide Pharmacokinetics and Pharmacodynamics in Gestational DiabetesNCT05482789 | Exenatide | Phase 4 | Recruiting | 13 | 2023-04-12 |
| A Research Study to See How Well CagriSema Helps People in East Asia With Excess Body Weight Lose WeightNCT05813925 | Cagrilintide | Phase 3 | Completed | 331 | 2023-04-03 |
| REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood VesselsNCT05669755 | Cagrilintide | Phase 3 | Active not recruiting | 7101 | 2023-03-01 |
| Clinical Study of 18F-Exendin-4 in InsulinomaNCT07340437 | Exenatide | — | Completed | 20 | 2023-02-01 |
| A Research Study to See How Well CagriSema Helps People With Type 2 Diabetes and Excess Body Weight Lose WeightNCT05394519 | Cagrilintide | Phase 3 | Completed | 1200 | 2023-02-01 |
| A Research Study Comparing Wegovy to Other Weight Management Drugs in People Living With Obesity in AmericaNCT05579249 | Liraglutide | Phase 4 | Completed | 500 | 2023-01-19 |
| Exenatide for Smoking Cessation and Prevention of Weight GainNCT05610800 | Exenatide | Phase 2 | Completed | 140 | 2022-12-07 |
| A Study of Tirzepatide (LY3298176) in Adult Participants With Type 2 Diabetes Switching From Dulaglutide (SURPASS-SWITCH)NCT05564039 | Dulaglutide | Phase 4 | Completed | 282 | 2022-11-30 |
| A Study of LY3437943 in Healthy Participants and Participants With Impaired Renal FunctionNCT05611957 | Retatrutide | Phase 1 | Completed | 29 | 2022-11-16 |
| A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose WeightNCT05567796 | Cagrilintide | Phase 3 | Active not recruiting | 3400 | 2022-11-01 |
| Semaglutide vs SitagliptinNCT05195944 | Semaglutide | Phase 4 | Active not recruiting | 58 | 2022-10-26 |
| A Study of LY3437943 in Chinese Participants With Obesity Or OverweightNCT05548231 | Retatrutide | Phase 1 | Completed | 32 | 2022-10-24 |
| A Study of Tirzepatide (LY3298176) on the Reduction on Morbidity and Mortality in Adults With ObesityNCT05556512 | Tirzepatide | Phase 3 | Active not recruiting | 15374 | 2022-10-11 |
| LIGHT-MCI Trial: GLP-1 Agonist, SGLT2 Inhibitor, and DPP-4 Inhibitor for MCI Remission in Type 2 DiabetesNCT05313529 | Liraglutide | — | Completed | 396 | 2022-10-08 |
| PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 DiabetesNCT05390892 | Liraglutide, Dulaglutide | Phase 4 | Recruiting | 6000 | 2022-09-26 |
| A Drug Interaction Study of Clarithromycin and LY3502970 in Healthy ParticipantsNCT05469126 | Orforglipron | Phase 1 | Completed | 26 | 2022-08-01 |
| A Drug-Drug Interaction (DDI) Study of LY3437943 in Obese ParticipantsNCT05445232 | Retatrutide | Phase 1 | Completed | 32 | 2022-07-08 |
| GLP-1 Analogue in Preventing Progression of Small Vessel Disease (GAPP-SVD)NCT05356104 | Exenatide | Phase 2 | Recruiting | 110 | 2022-05-25 |
| A Study of Two Different Formulations of LY3502970 in Healthy ParticipantsNCT05341089 | Orforglipron | Phase 1 | Completed | 39 | 2022-05-17 |
| Assessment of Pancreatic Beta Cell Mass and Function by Positron Emission Tomography Imaging in Human Diabetes MellitusNCT05662189 | Exenatide | — | Recruiting | 70 | 2022-03-15 |
| Adiponectin in Patients With Metabolic DisordersNCT07539584 | Liraglutide | — | Completed | 130 | 2022-03-01 |
| Effect of Glucagon and Glucagon-like Peptide-1 Co-agonism on Cardiac Function and Metabolism in Overweight Participants with Type 2 DiabetesNCT04307797 | Exenatide | Phase 4 | Completed | 10 | 2022-01-18 |
| A Study of LY3502970 in Japanese Participants With Type 2 Diabetes MellitusNCT05086445 | Orforglipron | Phase 1 | Completed | 62 | 2021-11-12 |
| A Multiple Dose Study of LY3502970 in Healthy ParticipantsNCT05051566 | Orforglipron | Phase 1 | Completed | 26 | 2021-09-16 |
| Identification and Clinical Relevance of an Oxytocin Deficient State (GLP1 Study)NCT04897802 | Exenatide | Phase 4 | Completed | 42 | 2021-09-13 |
| Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes StudyNCT05220917 | Liraglutide, Dulaglutide, Exenatide | — | Active not recruiting | 781430 | 2021-08-01 |
| GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose IntoleranceNCT04731272 | Dulaglutide | Phase 2 | Recruiting | 30 | 2021-07-16 |
| Comparison of Type 2 Diabetes Pharmacotherapy RegimensNCT05073692 | Exenatide | — | Completed | 241981 | 2021-07-01 |
| A Study of LY3437943 in Japanese Participants With Type 2 Diabetes Mellitus (T2DM)NCT04823208 | Retatrutide | Phase 1 | Completed | 64 | 2021-05-24 |
| A Study of LY3437943 in Participants Who Have Obesity or Are OverweightNCT04881760 | Retatrutide | Phase 2 | Completed | 338 | 2021-05-20 |
| A Study of LY3437943 in Participants With Type 2 DiabetesNCT04867785 | Retatrutide | Phase 2 | Completed | 281 | 2021-05-13 |
| Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)NCT04822181 | Semaglutide | Phase 3 | Active not recruiting | 1205 | 2021-04-01 |
| SCALE KIDS: Research Study to Look at How Well a New Medicine is at Lowering Weight in Children With ObesityNCT04775082 | Liraglutide | Phase 3 | Active not recruiting | 78 | 2021-03-04 |
| Brain Activation and Satiety in Children 2NCT04520490 | Exenatide | Phase 3 | Active not recruiting | 63 | 2021-01-28 |
| Effects of Exercise and GLP-1 Agonism on Muscle Microvascular Perfusion and Insulin Action in Adults With Metabolic SyndromeNCT04575844 | Liraglutide | Phase 4 | Recruiting | 80 | 2020-11-01 |
| Exenatide Once-weekly as a Treatment for Multiple System AtrophyNCT04431713 | Exenatide | Phase 2 | Completed | 50 | 2020-09-16 |
| A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 DiabetesNCT04255433 | Dulaglutide | Phase 3 | Completed | 13299 | 2020-05-29 |
| A Clinical Study of NLY01 in Patient's With Early Parkinson's DiseaseNCT04154072 | Exenatide | Phase 2 | Completed | 255 | 2020-02-27 |
| Exenatide Once Weekly Over 2 Years as a Potential Disease Modifying Treatment for Parkinson's DiseaseNCT04232969 | Exenatide | Phase 3 | Completed | 194 | 2020-01-20 |
| A Study of LY3437943 in Participants With Type 2 Diabetes Mellitus (T2DM)NCT04143802 | Retatrutide | Phase 1 | Completed | 72 | 2019-12-18 |
| A Study of LY3502970 in Healthy ParticipantsNCT03929744 | Orforglipron | Phase 1 | Completed | 133 | 2019-06-12 |
| A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 DiabetesNCT03811561 | Semaglutide | Phase 3 | Active not recruiting | 1500 | 2019-05-08 |
| Liraglutide Effect in Atrial FibrillationNCT03856632 | Liraglutide | Phase 4 | Active not recruiting | 60 | 2019-03-18 |
| A Safety Study of LY3437943 Given as a Single Injection in Healthy ParticipantsNCT03841630 | Retatrutide | Phase 1 | Completed | 45 | 2019-03-13 |
| Effect of Exercise and/or Liraglutide on Vascular Dysfunction and Insulin Sensitivity in Type 2 Diabetes ( ZQL007)NCT03883412 | Liraglutide | Phase 4 | Recruiting | 60 | 2019-02-28 |
| Glucagon-like Peptide-1 Receptor PET/CT in GLP-1R Related DiseaseNCT06725693 | Exenatide | — | Recruiting | 500 | 2019-02-01 |
| Effects of GLP-1 Agonists on CArdiac Steatosis Evaluated by Magnetic Resonance ImagingNCT03498001 | Liraglutide, Dulaglutide | — | Completed | 42 | 2018-04-16 |
| A Study for Comparison of Canagliflozin Versus Alternative Antihyperglycemic Treatments on Risk of Heart Failure Hospitalization and Amputation for Participants With Type 2 Diabetes Mellitus and the Subpopulation With Established Cardiovascular DiseaseNCT03492580 | Dulaglutide, Exenatide | — | Completed | 714582 | 2018-02-22 |
| The Cardiovascular Effect of GLP-1 Agonist, SGLT2 Inhibitor and Their CombinationNCT03878706 | Liraglutide, MOTS-c | — | Recruiting | 240 | 2017-11-03 |
| Efficacy and Safety of Exenatide in the Treatment of Hypothalamic Obesity After Craniopharyngioma TherapyNCT02860923 | Exenatide | Phase 3 | Completed | 42 | 2017-01-11 |
| Saxenda: Underlying Mechanisms and Clinical OutcomesNCT02944500 | Liraglutide | Phase 4 | Active not recruiting | 28 | 2016-11 |
| Pharmacogenomics of GLP1 Receptor AgonistsNCT05762744 | Exenatide | Phase 1 | Terminated | 63 | 2016-06-01 |
| Timely Detection of Treatment Emergent Serious and Non-serious Adverse Events for Saxenda® in Mexican PatientsNCT02773355 | Liraglutide | — | Completed | 27 | 2016-05-16 |
| GLP-1 and Hyperoxia for Organ Protection in Heart SurgeryNCT02673931 | Exenatide | — | Unknown | 1400 | 2016-02 |
| Extended Release Exenatide Versus Placebo In Diabetic Patients With Type 4 Cardiorenal SyndromeNCT02251431 | Exenatide | Phase 3 | Completed | 57 | 2015-11 |
| Liver and Fat Regulation in Overweight Adolescent GirlsNCT02157974 | Exenatide | Phase 2/Phase 3 | Completed | 92 | 2014-08 |
| Effect of Victoza on Dietary Preferences and Habit in Patients With Type 2 DiabetesNCT02674893 | Liraglutide | Phase 4 | Terminated | 48 | 2014-02-04 |
| GLP-1's Effect on Cardiac Parameters and Mesenteric Blood FlowNCT01988545 | Exenatide | — | Completed | 8 | 2013-11-01 |
| A Comparative Effectiveness Study of Major Glycemia-lowering Medications for Treatment of Type 2 DiabetesNCT01794143 | Liraglutide | Phase 3 | Completed | 7850 | 2013-05 |
| Effect of Liraglutide on Fatty Liver Content and Lipoprotein MetabolismNCT02721888 | Liraglutide | Phase 4 | Terminated | 127 | 2012-07-10 |
| Effect of GLP-1 Receptor (GLP-1R) Agonists on Cardiac Function and on Epicardial Adipose Tissue (EAT) Volume and on Myocardial TG Content in Obese DiabeticsNCT02042664 | Exenatide | Phase 3 | Completed | 44 | 2011-01 |
| Durability of Combination Therapy With Exenatide/Pioglitazone/Metformin vs. Conventional Therapy in New Onset T2DMNCT01107717 | Exenatide | Phase 4 | Completed | 318 | 2009-01 |
| Islet Transplantation in Type 1 Diabetic Patients Using the University of Illinois at Chicago (UIC) ProtocolNCT00679042 | Exenatide | Phase 3 | Active not recruiting | 21 | 2007-09-05 |
| GLP-1 Receptor Agonists and Alzheimer's Disease: A Multi-National Target Trial EmulationNCT07677865 | Liraglutide | — | Completed | 213891 | 2007-01-01 |
| Pre-approval Expanded Access of Retatrutide (LY3437943)NCT07629401 | Retatrutide | — | Available | — | — |