| Metabolic Surgery for Atrial Fibrillation EliminationNCT07027969 · Ali Aminian | LiraglutideDulaglutide | Phase 4 | Not yet recruiting | 100 | 2026-11-01 |
| Phase II Study of Switching From Dulaglutide to PG-102(MG12) in Type 2 Diabetes MellitusNCT07677891 · ProGen. Co., Ltd. | Dulaglutide | Phase 2 | Not yet recruiting | 60 | 2026-10 |
| A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 DiabetesNCT07668336 · Eli Lilly and Company | DulaglutideOrforglipron | Phase 3 | Not yet recruiting | 170 | 2026-09 |
| A Research Study to Compare Two Different Versions of Injectable CagriSema in People With Type 2 DiabetesNCT07357740 · Novo Nordisk A/S | SemaglutideCagrilintide | Phase 2 | Withdrawn | 0 | 2026-08-27 |
| A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 DiabetesNCT07282613 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Not yet recruiting | 80 | 2026-08-04 |
| An Open-Label Tirzepatide Trial for Comorbid Obesity and Stimulant Use DisorderNCT07693608 · University of Texas Southwestern Medical Center | Tirzepatide | Phase 2 | Not yet recruiting | 45 | 2026-08-01 |
| Clinical Study of Local and Systemic Biological Impact of GLP1/GIP-Receptor Agonists in Patients With Breast Cancer: The CLARA TrialNCT07676331 · Universitaire Ziekenhuizen KU Leuven | Tirzepatide | Phase 2 | Not yet recruiting | 168 | 2026-08-01 |
| Tirzepatide in the Treatment of Cannabis Use DisorderNCT07671248 · McMaster University | Tirzepatide | Phase 3 | Not yet recruiting | 15 | 2026-08-01 |
| A Randomized, Double-blind, Placebo-controlled Study Evaluating the Effect of LAE102 Injection in Combination With Tirzepatide on Body in Obese ParticipantsNCT07671391 · Shanghai Zhongshan Hospital | Tirzepatide | Phase 2 | Not yet recruiting | 60 | 2026-08 |
| GLP-1 Receptor Agonists and Early Proctologic Effects in Morbid ObesityNCT07668765 · Gazi University | Tirzepatide | — | Not yet recruiting | 100 | 2026-08 |
| Imaging in Semaglutide StudyNCT07695454 · The Cleveland Clinic | Semaglutide | — | Not yet recruiting | 10 | 2026-07-15 |
| GLP-1 RA Plus SOC Treatment in First-line, Metastatic Pancreatic, Colorectal, or Hepatocellular CancerNCT07627191 · University of Arizona | Semaglutide | EARLY_Phase 1 | Not yet recruiting | 30 | 2026-07-10 |
| A Study of Weight Loss Intervention With Tirzepatide and Progestin Intrauterine Device to Treat Endometrial Hyperplasia and Grade 1 Endometrial CancerNCT07349641 · National Cancer Institute (NCI) | Tirzepatide | Phase 2 | Not yet recruiting | 55 | 2026-07-06 |
| Free Fatty Acid Effects In Type 2 DiabetesNCT07677995 · University of Ulster | Semaglutide | — | Enrolling by invitation | 60 | 2026-07 |
| Safety, Tolerability and Efficacy of Semaglutide Depot in Subjects With Type-2 Diabetes MellitusNCT07563699 · Mapi Pharma Ltd. | Semaglutide | Phase 1/Phase 2 | Not yet recruiting | 24 | 2026-07 |
| Safety, Tolerability and Pharmacokinetics of a Subcutaneous Semaglutide ImplantNCT07430059 · Vivani Medical, Inc | Semaglutide | Phase 1 | Not yet recruiting | 20 | 2026-07 |
| Tirzepatide Following Adrenalectomy in Mild Autonomous Cortisol SecretionNCT07573163 · Alaa Sada | Tirzepatide | Phase 2 | Not yet recruiting | 34 | 2026-07 |
| A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes Who Observe Ramadan FastingNCT07613307 · Eli Lilly and Company | Orforglipron | Phase 3 | Not yet recruiting | 130 | 2026-07 |
| A Research Study to Compare Different Versions of Injectable CagriSema and Placebo in People With Excess Body WeightNCT07357766 · Novo Nordisk A/S | SemaglutideCagrilintide | Phase 3 | Withdrawn | 0 | 2026-06-22 |
| Tirzepatide to Reduce rEcurrence And Burden After Ablation of Atrial FibrillationNCT07382024 · National Taiwan University Hospital | Tirzepatide | — | Not yet recruiting | 200 | 2026-06-16 |
| Brain Plasticity and GLP-1 Receptor Agonist Treatment for ObesityNCT07021937 · University of Colorado, Denver | Semaglutide | Phase 3 | Not yet recruiting | 120 | 2026-06-15 |
| Semaglutide Delivered Epi-Intradermally by Microarray Patch (VX-201) Versus Subcutaneous Administration in Healthy Overweight and Obese ParticipantsNCT07673900 · Terrestrial Bio, Inc. | Semaglutide | Phase 1 | Recruiting | 62 | 2026-06-15 |
| Tirzepatide in MetALDNCT07046819 · National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Tirzepatide | Phase 2 | Recruiting | 120 | 2026-06-11 |
| A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With ObesityNCT07639021 · Novo Nordisk A/S | Semaglutide | Phase 2 | Recruiting | 230 | 2026-06-09 |
| Tirzepatide's Role in Postmenopausal HR+ Breast Cancer SurvivorsNCT07257484 · Weill Medical College of Cornell University | Tirzepatide | Phase 4 | Recruiting | 30 | 2026-06-08 |
| Assessing Biological Aging in a Real-World Medical Weight Loss Program Using the LinAge2 Clinical ClockNCT07444073 · National University of Singapore | SemaglutideTirzepatide | — | Not yet recruiting | 440 | 2026-06-01 |
| Clinical and Neurobehavioral Changes With Weight Loss Drug Discontinuation and ReinitiationNCT07387796 · The University of Texas at Dallas | Tirzepatide | — | Recruiting | 40 | 2026-06 |
| Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse EventsNCT07607587 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Recruiting | 114 | 2026-05-29 |
| Genetic, Microbiological and Behavioral Factors in ObesityNCT07650149 · Jan Kochanowski University | Tirzepatide | — | Recruiting | 200 | 2026-05-23 |
| A Phase 2a Study of ALN-PNP With and Without a GLP1R Agonist in Adult Patients With Homozygous PNPLA3-Related MASLDNCT07527910 · Regeneron Pharmaceuticals | Tirzepatide | Phase 2 | Recruiting | 204 | 2026-05-22 |
| A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose WeightNCT07564414 · Novo Nordisk A/S | SemaglutideCagrilintide | Phase 3 | Recruiting | 2500 | 2026-05-21 |
| Tirzepatide s Dopaminergic Effects in Alcohol Use Disorders (AUD)NCT07559500 · National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Tirzepatide | Phase 1 | Recruiting | 176 | 2026-05-20 |
| A Research Study to Compare Blood Levels of Two Different Versions of Cagrilintide in Adults With Excess Body WeightNCT07605052 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Active not recruiting | 50 | 2026-05-20 |
| Phase 3 Study of LUM-201 in Children With Growth Hormone DeficiencyNCT06948214 · Lumos Pharma | MK-677 | Phase 3 | Recruiting | 150 | 2026-05-20 |
| A Research Study to Compare Blood Levels of Cagrilintide After Multiple Doses of Different Versions of Cagrilintide in Adults With Overweight or ObesityNCT07597018 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Recruiting | 234 | 2026-05-18 |
| Recombinant Human Thymosin Beta 4 for Injection(NL005) for Acute Myocardial InfarctionNCT07586865 · Beijing Northland Biotech. Co., Ltd. | Thymosin Beta-4 | Phase 2 | Not yet recruiting | 189 | 2026-05-18 |
| Tirzepatide Titration to Reduce Side Effects in Individuals With ObesityNCT07574723 · Dasman Diabetes Institute | Tirzepatide | — | Recruiting | 68 | 2026-05-15 |
| TP04HN106 in the Treatment of Patients With Amyotrophic Lateral SclerosisNCT06726577 · Talengen Institute of Life Sciences, Shenzhen, P.R. China. | Liraglutide | Phase 1/Phase 2 | Recruiting | 60 | 2026-05-10 |
| RWS of of Liraglutide Alone and in Combination With Orlistat for Weight Loss in Overweight/Obese Patients.NCT07301437 · The Fourth Affiliated Hospital of Zhejiang University School of Medicine | Liraglutide | Phase 4 | Not yet recruiting | 120 | 2026-05-01 |
| Efficacy and Safety of Triple Therapy With Dulaglutide, SGLT2 Inhibitors, and Finerenone in Chinese Adults With Type 2 Diabetes and Chronic Kidney DiseaseNCT07537088 · First Affiliated Hospital of Wannan Medical College | Dulaglutide | Phase 4 | Not yet recruiting | 468 | 2026-05 |
| A Research Study Looking Into How Cagrilintide Influences Food Intake and Appetite in People With Overweight or ObesityNCT07557953 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Recruiting | 120 | 2026-04-30 |
| Targeting Agonists of Glucagon-like Peptide-1 Receptor for Multiple SclerosisNCT07497399 · Johns Hopkins University | Exenatide | Phase 2 | Recruiting | 120 | 2026-04-28 |
| Precision Obesity Medicine: Genetic Prediction of Response to GLP-1/GIP Agonists.NCT07653412 · National and Kapodistrian University of Athens | SemaglutideTirzepatide | — | Recruiting | 220 | 2026-04-22 |
| A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 DiabetesNCT07415954 · Novo Nordisk A/S | Semaglutide | Phase 2 | Recruiting | 270 | 2026-04-17 |
| Understanding the Effect of CagriSema, Cagrilintide, and Semaglutide on Muscle Health (Role of Amylin Signature in Muscle Health)NCT07527195 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Recruiting | 100 | 2026-04-10 |
| A Study to Estimate Early Clinical Efficacy Signals of GLP-1 Agonist Administration in Conjunction With Levonorgestrel Intrauterine Device in Obese Patients With Endometrioid Intraepithelial NeoplasiaNCT07107334 · University of Florida | LiraglutideOrforglipron | Phase 2 | Recruiting | 20 | 2026-04-07 |
| Proof-of-Concept Study Evaluating Total Body Weight, Physical Function & Safety of Enobosarm in Patients Treated With GLP-1 Receptor Agonist, for Weight LossNCT07446998 · Veru Inc. | Semaglutide | Phase 2 | Recruiting | 200 | 2026-03-26 |
| A Study to Evaluate ALN-2232 in Participants With ObesityNCT07463846 · Alnylam Pharmaceuticals | Tirzepatide | Phase 1/Phase 2 | Recruiting | 156 | 2026-03-02 |
| Comparison of the Effects of General Anesthesia and Combined Spinal-Epidural Anesthesia on Ferroptosis, Humanin and MOTS-c Levels in Renal TransplantationNCT07678073 · University of Gaziantep | MOTS-c | — | Recruiting | 68 | 2026-03-01 |
| Evaluation of Facial and Neck Skin Laxity With SofWave Treatment in Adults Initiating Tirzepatide for Weight LossNCT07685834 · Sofwave Medical LTD | Tirzepatide | — | Active not recruiting | 30 | 2026-02-27 |
| Effect of LY3437943 Versus Placebo in Participants Who Have Obesity or Are OverweightNCT07467447 · Hudson Biotech | Retatrutide | Phase 2 | Recruiting | 300 | 2026-02-15 |
| The Evira Study: Additional Support During Obesity TreatmentNCT06836284 · Karolinska Institutet | Liraglutide | — | Recruiting | 40 | 2026-02-13 |
| Tirzepatide vs Semaglutide in Individuals at Cardiovascular Risk But Without Diabetes.NCT07619508 · Brigham and Women's Hospital | SemaglutideTirzepatide | — | Completed | 100000 | 2026-02-10 |
| A Study Looking at How Weekly Injections of Two Hormones - GIP and Amylin - Affect Stomach-related Side Effects in People Who Are Overweight or ObeseNCT07411560 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Recruiting | 100 | 2026-02-09 |
| TB-500 (Thymosin Beta 4 17-23 Fragment) for Cardiovascular Biomarkers in Stable ASCVDNCT07487363 · Hudson Biotech | TB-500Thymosin Beta-4 | Phase 1/Phase 2 | Recruiting | 80 | 2026-02-05 |
| Emulation of the REWIND Cardiovascular Outcomes Trial in Healthcare Claims Data.NCT07417631 · Brigham and Women's Hospital | Dulaglutide | — | Completed | 300000 | 2026-02-03 |
| BPC 157 for Acute Hamstring Muscle Strain RepairNCT07437547 · Hudson Biotech | BPC-157 | Phase 2 | Recruiting | 120 | 2026-02-02 |
| Tesamorelin for Reduction of Liver Fat in Adults With Fatty Liver Disease (Mock Study)NCT07481734 · Hudson Biotech | Tesamorelin | Phase 2 | Recruiting | 120 | 2026-02-02 |
| MOTS-c for Improving Insulin Sensitivity in Adults With Prediabetes and Overweight/ObesityNCT07505745 · Hudson Biotech | MOTS-c | Phase 2 | Recruiting | 120 | 2026-02-02 |
| INcreTin-based thERapies for Cardiovascular Event PrevenTion in Patients With and Without ASCVD (INTERCEPT-ASCVD)NCT07417618 · Brigham and Women's Hospital | SemaglutideTirzepatideDulaglutide | — | Completed | 60000 | 2026-01-27 |
| Comparative Effectiveness of Oral Semaglutide vs Sitagliptin Among Individuals With Heart Failure With Preserved Ejection Fraction (STEP-HFpEF DM ORAL)NCT07390110 · Brigham and Women's Hospital | Semaglutide | — | Active not recruiting | 25664 | 2026-01-24 |
| A Study of Retatrutide (LY3437943) in Participants Without Type 2 Diabetes Who Have Obesity or OverweightNCT07357415 · Eli Lilly and Company | Retatrutide | Phase 3 | Active not recruiting | 600 | 2026-01-24 |
| Injectable Semaglutide vs Dulaglutide in Individuals at Cardiovascular RiskNCT07619495 · Brigham and Women's Hospital | SemaglutideDulaglutide | — | Completed | 120000 | 2026-01-20 |
| A Single-Center, Open-Label, Single Ascending Dose Study of Exenatide Circular RNA-Lipid Nanoparticle Injection (CR059) in Chinese Subjects With Type 2 Diabetes MellitusNCT07347080 · The First Affiliated Hospital of Henan University of Science and Technology | Exenatide | EARLY_Phase 1 | Recruiting | 9 | 2026-01-20 |
| A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body WeightNCT07253285 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Recruiting | 460 | 2026-01-08 |
| Estimating the Impact of Obesity Medications on Clinical and Economic OutcomesNCT07640139 · Indiana University | Liraglutide | — | Enrolling by invitation | 125000 | 2026-01-01 |
| A Study to Evaluate the Effect of Fasting Duration and Dulaglutide (LY2189265) Withholding on Gastric Retention in Participants With Type 2 Diabetes MellitusNCT07313813 · Eli Lilly and Company | Dulaglutide | Phase 1 | Active not recruiting | 20 | 2025-12-29 |
| Role of GLP1 RA Dulaglutide on Severe Intracranial AtherosclerosisNCT07282041 · National University of Singapore | Dulaglutide | Phase 2/Phase 3 | Recruiting | 130 | 2025-12-17 |
| Impact of Discontinuing GLP-1 Receptor Agonists for Two Weeks Prior to Upper Endoscopy on the Risk of Gastric RetentionNCT07276763 · Fudan University | Dulaglutide | — | Not yet recruiting | 16509 | 2025-12-10 |
| A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)NCT07241390 · Eli Lilly and Company | Orforglipron | Phase 3 | Recruiting | 7140 | 2025-12-01 |
| A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants With Obesity and Without Diabetes (SURMOUNT-REAL UK)NCT07247084 · Eli Lilly and Company | Tirzepatide | Phase 4 | Recruiting | 3000 | 2025-11-24 |
| A Study of Retatrutide (LY3437943) in Participants With Obesity or OverweightNCT07232719 · Eli Lilly and Company | Retatrutide | Phase 3 | Active not recruiting | 250 | 2025-11-17 |
| Effects of Tirzepatide on Weight Loss and Chronic Inflammation in People With HIVNCT06935838 · University of Hawaii | Tirzepatide | Phase 2 | Completed | 12 | 2025-11-12 |
| Examination of How the Duration of Fasting and Temporary Stopping of GLP-1 Medications Affect the Amount of Food Left in the Stomach in People Using Liraglutide (Injected), Semaglutide (Taken by Mouth) or Semaglutide (Injected)NCT07225816 · Novo Nordisk A/S | Liraglutide | Phase 1 | Recruiting | 75 | 2025-11-07 |
| Weight Loss in People Living With Overweight or Obesity Following Treatment With CagrilintideNCT07220642 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Active not recruiting | 300 | 2025-11-05 |
| Weight Loss in People Living With Overweight or Obesity and Type 2 Diabetes Following Treatment With CagrilintideNCT07220759 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Active not recruiting | 330 | 2025-11-05 |
| Efficacy and Safety of Orforglipron in Participants With Peripheral Artery DiseaseNCT07223593 · Eli Lilly and Company | Orforglipron | Phase 3 | Recruiting | 1205 | 2025-10-31 |
| A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)NCT07165028 · Eli Lilly and Company | TirzepatideRetatrutide | Phase 3 | Recruiting | 4500 | 2025-10-15 |
| A Phase 3 Study of HS-20094 in Patients With T2DMNCT07156539 · Jiangsu Hansoh Pharmaceutical Co., Ltd. | Dulaglutide | Phase 3 | Not yet recruiting | 546 | 2025-09-30 |
| A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or OverweightNCT07202884 · Eli Lilly and Company | Orforglipron | Phase 3 | Recruiting | 1000 | 2025-09-30 |
| A Study to See How Metabolism is Influenced by Weight Loss Due to Intervention With Cagrilintide and Semaglutide Compared to DietNCT07184086 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Recruiting | 80 | 2025-09-26 |
| Study of Tirzepatide for Recovery and Alcohol Use ManagementNCT06727331 · Brigham and Women's Hospital | Tirzepatide | Phase 2 | Recruiting | 20 | 2025-09-15 |
| Using Secondary Data to Evaluate Sex-based Heterogeneity of GLP-1 Agonists and SGLT2 Inhibitors on Cardiovascular-Kidney-Metabolic Health (CKMH) Outcomes in Real-world Settings (DASH-CKMH)NCT07188545 · Ohio State University | DulaglutideExenatide | — | Active not recruiting | 23280000 | 2025-09-15 |
| A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the KneeNCT07153471 · Eli Lilly and Company | Orforglipron | Phase 3 | Recruiting | 800 | 2025-09-15 |
| A Study to Compare Different Doses of RO7795081 With a Placebo or Semaglutide in People With Type 2 DiabetesNCT07112872 · Hoffmann-La Roche | Semaglutide | Phase 2 | Active not recruiting | 240 | 2025-08-19 |
| Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Therapy and Exercise Training in People With ObesityNCT07091500 · Washington University School of Medicine | Semaglutide | — | Recruiting | 40 | 2025-08-11 |
| Role of Glucagon-like Peptide-1 Receptor Agonists in Menstrual Irregularities in Adolescent Females With Type 1 Diabetes MellitusNCT07319286 · Ain Shams University | Dulaglutide | Phase 1/Phase 2 | Enrolling by invitation | 50 | 2025-08-04 |
| Bone Metabolism in 12-21 Year Olds Undergoing Glucagon Like Peptide (GLP)-1 Receptor Agonist TherapyNCT06903923 · University of Virginia | Liraglutide | Phase 2 | Recruiting | 120 | 2025-07-31 |
| Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIVNCT06554717 · Massachusetts General Hospital | SermorelinTesamorelin | Phase 2 | Recruiting | 100 | 2025-07-10 |
| Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or OverweightNCT06937099 · Eli Lilly and Company | Tirzepatide | Phase 3 | Recruiting | 290 | 2025-06-26 |
| Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b StudyNCT06937086 · Eli Lilly and Company | Tirzepatide | Phase 3 | Recruiting | 350 | 2025-06-26 |
| A Trial to Investigate the Safety and Efficacy of Intra-articular 4P004 Injection in Subjects With Knee Synovitis and OsteoarthritisNCT07225829 · 4Moving Biotech | Liraglutide | Phase 2 | Recruiting | 129 | 2025-06-17 |
| The Role of the Amylin Analogue Cagrilintide in Bone MetabolismNCT07010432 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Recruiting | 144 | 2025-06-12 |
| A Study to Investigate the Response of Participants With Type 2 Diabetes Mellitus on Once-Weekly Retatrutide to HypoglycemiaNCT06982846 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 80 | 2025-06-06 |
| A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-termNCT07011667 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Active not recruiting | 609 | 2025-06-03 |
| A Study to Evaluate the Effect of Retatrutide on Insulin Secretion and Insulin Sensitivity in Adult Participants With Type 2 Diabetes MellitusNCT06982859 · Eli Lilly and Company | Retatrutide | Phase 1 | Recruiting | 95 | 2025-06-02 |
| A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back PainNCT07035093 · Eli Lilly and Company | Retatrutide | Phase 3 | Recruiting | 586 | 2025-05-29 |
| Impact of Pharmacogenetic-Guided Treatment on Type 2 Diabetes.NCT06851962 · Fundación para la Investigación del Hospital Clínico de Valencia | Dulaglutide | Phase 4 | Active not recruiting | 504 | 2025-05-26 |
| Tirzepatide vs Liraglutide in BoneNCT07094568 · National and Kapodistrian University of Athens | Liraglutide | — | Recruiting | 72 | 2025-05-23 |
| A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Type 2 DiabetesNCT06972472 · Eli Lilly and Company | Orforglipron | Phase 3 | Active not recruiting | 600 | 2025-05-19 |
| A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight With and Without Type 2 DiabetesNCT06993792 · Eli Lilly and Company | Orforglipron | Phase 3 | Active not recruiting | 1200 | 2025-05-15 |
| A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and at Least One Weight-Related ComorbidityNCT06972459 · Eli Lilly and Company | Orforglipron | Phase 3 | Active not recruiting | 600 | 2025-05-15 |
| A First-In-Human Study of ARO-ALK7 in Adults With Obesity With and Without Type 2 Diabetes MellitusNCT06937203 · Arrowhead Pharmaceuticals | Tirzepatide | Phase 1/Phase 2 | Recruiting | 150 | 2025-05-09 |
| Liraglutide Treatment in Patients With Maturity-onset Diabetes of the Young (MODY)NCT07029009 · Mansa | Liraglutide | Phase 2 | Recruiting | 50 | 2025-05-08 |
| A Two-year Prospective, Observational Study of Wegovy in Real-world Clinical PracticeNCT07055607 · Novo Nordisk A/S | Semaglutide | — | Enrolling by invitation | 1250 | 2025-05-01 |
| A Study of HDM1005 in Participants With T2DM Not Controlled With Diet/Exercise or MetforminNCT07109700 · Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | Dulaglutide | Phase 2 | Recruiting | 216 | 2025-04-30 |
| A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1NCT06948435 · Eli Lilly and Company | Orforglipron | Phase 3 | Active not recruiting | 487 | 2025-04-30 |
| A Master Protocol for Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight: (ATTAIN-Hypertension Screening)NCT06948422 · Eli Lilly and Company | Orforglipron | Phase 3 | Active not recruiting | 974 | 2025-04-30 |
| A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL2NCT06952530 · Eli Lilly and Company | Orforglipron | Phase 3 | Active not recruiting | 487 | 2025-04-30 |
| A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or TirzepatideNCT06897475 · Eli Lilly and Company | SemaglutideTirzepatide | Phase 2 | Recruiting | 240 | 2025-03-28 |
| Effect of Tirzepatide on Brown Adipose Tissue in ObesityNCT06893211 · University Medical Centre Ljubljana | Tirzepatide | Phase 2 | Completed | 34 | 2025-03-18 |
| A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)NCT06864026 · Eli Lilly and Company | Tirzepatide | Phase 4 | Recruiting | 200 | 2025-03-06 |
| A Study of Retatrutide (LY3437943) in the Maintenance of Weight Reduction in Individuals With ObesityNCT06859268 · Eli Lilly and Company | Retatrutide | Phase 3 | Active not recruiting | 643 | 2025-03-05 |
| A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or OverweightNCT06824051 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 120 | 2025-02-17 |
| A Research Study to Look Into the Long-term Effect on Weight Loss of CagriSema in People With ObesityNCT06780449 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Active not recruiting | 400 | 2025-02-10 |
| To Investigate the Effect of Retatrutide (LY3437943) on Metoprolol Pharmacokinetics in Healthy ParticipantsNCT06808802 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 30 | 2025-02-03 |
| A Research Study to Investigate the Effects of CagriSema Compared to Placebo in People With Type 2 Diabetes and Painful Diabetic Peripheral NeuropathyNCT06797869 · Novo Nordisk A/S | Cagrilintide | Phase 2 | Active not recruiting | 142 | 2025-01-29 |
| A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)NCT06739122 · Eli Lilly and Company | Dulaglutide | Phase 3 | Recruiting | 55 | 2025-01-10 |
| Tirzepatide-Based Prehabilitation Before Elective Ventral and Incisional Hernia Repair in Patients With ObesityNCT07638592 · Azienda Sanitaria Locale Napoli 2 Nord | Tirzepatide | — | Completed | 91 | 2025-01-01 |
| Beta Cell Function in Type 2 Diabetes: Differential Effects of SGLT2 Inhibitors and GLIP-Receptor AgonistsNCT07325435 · MaryAnn Banerji | LiraglutideDulaglutide | Phase 4 | Active not recruiting | 60 | 2024-12-21 |
| Assessment of Safety, Tolerability and Drug Levels of Exenatide ImplantNCT05670379 · Vivani Medical, Inc | Exenatide | Phase 1 | Completed | 24 | 2024-12-20 |
| A Drug-Drug Interaction Study of Orforglipron (LY3502970) With Quinidine in Healthy ParticipantsNCT06704763 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 27 | 2024-12-06 |
| A First-In-Human Study of ARO-INHBE in Adults With Obesity With and Without Type 2 Diabetes MellitusNCT06700538 · Arrowhead Pharmaceuticals | Tirzepatide | Phase 1/Phase 2 | Recruiting | 180 | 2024-12-04 |
| A Research Study to Compare Blood Levels of Cagrilintide and Semaglutide After Single Doses of Different Versions of Injectable CagriSema in Adults With Overweight or ObesityNCT06716307 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Completed | 18 | 2024-12-02 |
| Glucagon-Like Peptide 1 Receptor Agonist in Diabetes Mellitus Management in Children and Adolescents With Transfusion-Dependent ThalassemiaNCT07370922 · Ain Shams University | Dulaglutide | Phase 2 | Completed | 80 | 2024-11-22 |
| A Study of Orforglipron (LY3502970) in Adolescent Participants With Obesity, or Overweight With Related ComorbiditiesNCT06672939 · Eli Lilly and Company | Orforglipron | Phase 3 | Recruiting | 150 | 2024-11-18 |
| A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)NCT06672549 · Eli Lilly and Company | Orforglipron | Phase 3 | Recruiting | 125 | 2024-11-18 |
| A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or BothNCT06534411 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Active not recruiting | 1023 | 2024-11-05 |
| A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have ObesityNCT06662383 · Eli Lilly and Company | Retatrutide | Phase 3 | Active not recruiting | 800 | 2024-11-01 |
| Comparative Study of Tirzepatide Versus Dulaglutide (SURPASS CVOT) or Semaglutide on Major Cardiovascular Events in Participants With Type 2 DiabetesNCT06779929 · Brigham and Women's Hospital | Dulaglutide | — | Completed | 70000 | 2024-11-01 |
| A Master Protocol for Orforglipron in Participants With Obstructive Sleep Apnea and Obesity or OverweightNCT06649045 · Eli Lilly and Company | Orforglipron | Phase 3 | Active not recruiting | 600 | 2024-10-22 |
| Food (Poly)Phenol Metabotypes and Beta-cell Mass and Function.NCT06888167 · Azienda Ospedaliero-Universitaria di Parma | Exenatide | — | Recruiting | 40 | 2024-10-14 |
| Residual Gastric Content After Holding of Glucagon-like Peptide-1 Receptor Agonists Before Elective SurgeryNCT06500143 · Ciusss de L'Est de l'Île de Montréal | Dulaglutide | — | Completed | 94 | 2024-10-09 |
| A Study in People With Obesity to Test the Effects of BI 456906 Compared With Semaglutide on Glucagon Receptor Activity in the LiverNCT05202353 · Boehringer Ingelheim | Semaglutide | Phase 1 | Recruiting | 30 | 2024-10-01 |
| Comparative Effectiveness of Tirzepatide and Semaglutide in Individuals at Cardiovascular RiskNCT07096063 · Brigham and Women's Hospital | Dulaglutide | — | Completed | 887132 | 2024-10-01 |
| Prediction of the SURPASS-CVOT Cardiovascular Outcome Trial in Healthcare Claims DataNCT07088718 · Brigham and Women's Hospital | Dulaglutide | — | Completed | 44671 | 2024-10-01 |
| Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Moderate-to-Severe Plaque Psoriasis and Obesity or OverweightNCT06588283 · Eli Lilly and Company | Tirzepatide | Phase 3 | Completed | 281 | 2024-09-30 |
| A Pan-European Post-Authorisation Safety Study: Risk of Pancreatic Cancer Among Type 2 Diabetes Patients Who Initiated Exenatide as Compared With Those Who Initiated Other Non-Glucagon-Like Peptide 1 Receptor Agonists Based Glucose Lowering DrugsNCT05663515 · AstraZeneca | Exenatide | — | Recruiting | 24000 | 2024-09-30 |
| Effects of RDX-002 on Postprandial Triglycerides in Patients Discontinuing GLP-1 AgonistsNCT06640972 · Response Pharmaceuticals | SemaglutideTirzepatide | Phase 2 | Completed | 68 | 2024-09-27 |
| Obesity Management for Kidney TRANSPLANTation: OK-TRANSPLANT 2NCT06396416 · Western University, Canada | Semaglutide | Phase 4 | Recruiting | 60 | 2024-09-26 |
| A Study of Orforglipron for the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-MAINTAIN)NCT06584916 · Eli Lilly and Company | Orforglipron | Phase 3 | Completed | 376 | 2024-09-13 |
| Real-World Evaluation of Omarigliptin for Type 2 Diabetes Meliitus in BangladeshNCT06449235 · Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders | Exenatide | Phase 4 | Not yet recruiting | 938 | 2024-09 |
| Exenatide For Reducing the Reinforcing Effects of CocaineNCT06252623 · Christopher D. Verrico | Exenatide | Phase 1 | Withdrawn | 0 | 2024-08-01 |
| Holding vs. Continuing Incretin-based Therapies Before Upper EndoscopyNCT06533527 · The Cleveland Clinic | Dulaglutide | Phase 4 | Completed | 69 | 2024-07-31 |
| A Phase 3 Study to Evaluate the Efficacy of JY09 Compared With Dulaglutide in Combination Therapy Diabetes Mellitus Type 2 Patients With MetforminNCT06257966 · Beijing Dongfang Biotech Co., Ltd. | DulaglutideExenatide | Phase 3 | Active not recruiting | 600 | 2024-07-17 |
| A Phase 3 Study to Evaluate the Efficacy of JY09 Compared With Placebo in T2DM PatientsNCT06254014 · Beijing Dongfang Biotech Co., Ltd. | Exenatide | Phase 3 | Active not recruiting | 270 | 2024-07-10 |
| Risk Factors Affect Weight Loss Outcomes After Treatment.NCT06482411 · E-DA Hospital | Liraglutide | — | Completed | 3602 | 2024-06-27 |
| A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose WeightNCT06388187 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Completed | 300 | 2024-06-24 |
| A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)NCT06439277 · Eli Lilly and Company | Tirzepatide | Phase 3 | Recruiting | 300 | 2024-06-03 |
| Diabetes Islet Preservation Immune TreatmentNCT02586831 · Camillo Ricordi and Jay Skyler | Exenatide | Phase 1/Phase 2 | Withdrawn | 0 | 2024-06-01 |
| Effects of NNC0194-0499, Cagrilintide, and Semaglutide Alone or in Combinations on Liver Damage and Alcohol Use in People With Alcohol-related Liver DiseaseNCT06409130 · Novo Nordisk A/S | Cagrilintide | Phase 2 | Completed | 270 | 2024-05-20 |
| Investigating How CagriSema, Semaglutide and Cagrilintide Regulate Insulin Effects in the Body of People With Type 2 DiabetesNCT06403761 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Completed | 158 | 2024-05-06 |
| The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)NCT06383390 · Eli Lilly and Company | Retatrutide | Phase 3 | Active not recruiting | 10000 | 2024-04-30 |
| Effect of Retatrutide Compared With Placebo in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone (TRANSCEND-T2D-1)NCT06354660 · Eli Lilly and Company | Retatrutide | Phase 3 | Completed | 537 | 2024-04-10 |
| Study to Evaluate the Safety and Effectiveness of Saxenda® for Weight Management in Routine Clinical Practice in Taiwan.NCT06283641 · Novo Nordisk A/S | Liraglutide | — | Completed | 300 | 2024-04-08 |
| A Study of TG103 Injection Combined With Metformin in Treatment of Type 2 Diabetes MellitusNCT06235086 · CSPC Baike (Shandong) Biopharmaceutical Co., Ltd. | Dulaglutide | Phase 3 | Completed | 632 | 2024-04-08 |
| A Research Study to See if Kidney Damage in People With Chronic Kidney Disease and Type 2 Diabetes Living With Overweight or Obesity Can be Reduced by CagriSema Compared to Semaglutide, Cagrilintide and PlaceboNCT06131372 · Novo Nordisk A/S | Cagrilintide | Phase 2 | Completed | 626 | 2024-04-01 |
| Use of Liraglutide in Children Aged 6 to 12 Years With Severe ObesityNCT07590219 · University of Sao Paulo General Hospital | Liraglutide | Phase 4 | Active not recruiting | 30 | 2024-03-30 |
| A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Once-daily Basal Insulin With or Without MetforminNCT06323161 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Completed | 274 | 2024-03-26 |
| A Study to Measure Calorie Consumption and Usage in Participants With Obesity Using LY3437943NCT06313528 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 85 | 2024-03-20 |
| GLP-1 Receptor Agonist for Reduction of Myocardial Injury After Non-cardiac SurgeryNCT06324461 · The University of Hong Kong | Dulaglutide | Phase 4 | Recruiting | 372 | 2024-03-20 |
| A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Diet and ExerciseNCT06323174 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Completed | 189 | 2024-03-19 |
| Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)NCT06297603 · Eli Lilly and Company | Retatrutide | Phase 3 | Active not recruiting | 320 | 2024-03-15 |
| GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGHNCT06003153 · Massachusetts General Hospital | Semaglutide | Phase 4 | Recruiting | 125 | 2024-03-12 |
| A Study on How CagriSema Affects Levels of Atorvastatin and Warfarin in the Blood of Participants With Excess Body WeightNCT06289504 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Completed | 34 | 2024-02-27 |
| A Research Study to Look at How CagriSema Influences Food Intake, Appetite and Emptying of the Stomach in People With Excess Body WeightNCT06207877 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Completed | 62 | 2024-02-23 |
| Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2)NCT06260722 · Eli Lilly and Company | Retatrutide | Phase 3 | Active not recruiting | 1250 | 2024-02-21 |
| A Study of How CagriSema Works on Appetite in People With Excess Body WeightNCT06267092 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Completed | 164 | 2024-02-15 |
| A Study of HS-20094 in Patients With T2DMNCT06901648 · Jiangsu Hansoh Pharmaceutical Co., Ltd. | Dulaglutide | Phase 2 | Completed | 275 | 2024-02-06 |
| Effect of Liraglutide in Obese Women With Polycystic Ovary SyndromeNCT05965908 · Beni-Suef University | Liraglutide | Phase 3 | Completed | 150 | 2024-01-30 |
| Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory IssuesNCT06171152 · University of Chicago | Liraglutide | EARLY_Phase 1 | Suspended | 30 | 2024-01-26 |
| A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 InhibitorNCT06221969 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Completed | 1024 | 2024-01-16 |
| A Study of Orforglipron (LY3502970) Compared With Dapagliflozin in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With MetforminNCT06192108 · Eli Lilly and Company | Orforglipron | Phase 3 | Completed | 962 | 2024-01-10 |
| A Drug-Drug Interaction Study of Orforglipron (LY3502970) in Healthy Overweight and Obese ParticipantsNCT06186622 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 50 | 2024-01-02 |
| Association of Gene Polymorphism With Susceptibility to T2DM and the Therapeutic Responses to Exenatide in Chinese Patients With T2DMNCT06256419 · The Affiliated Hospital of Xuzhou Medical University | Exenatide | — | Recruiting | 300 | 2024-01-01 |
| Pharmacological Treatment - An Overview of Its Role in Managing Childhood ObesityNCT07304141 · Göteborg University | Liraglutide | — | Completed | 128 | 2023-12-20 |
| Phase 2 Study of HEC88473 Injection in Subjects With Type 2 Diabetes MellitusNCT06148649 · Dongguan HEC Biopharmaceutical R&D Co., Ltd. | Dulaglutide | Phase 2 | Completed | 234 | 2023-12-10 |
| A Research Study to See How Well CagriSema Compared to Tirzepatide Helps People With Obesity Lose WeightNCT06131437 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Completed | 809 | 2023-11-27 |
| A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or OverweightNCT06143956 · Eli Lilly and Company | Tirzepatide | Phase 2 | Recruiting | 1481 | 2023-11-17 |
| A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes and Inadequate Glycemic Control With Insulin Glargine, With or Without Metformin and/or SGLT-2 InhibitorNCT06109311 · Eli Lilly and Company | Orforglipron | Phase 3 | Completed | 546 | 2023-11-10 |
| Influence of JY09 on Pharmacokinetics of Metformin , Rosuvastatin , and Digoxin and the QT Interval Study in Overweight Chinese SubjectsNCT06247748 · Beijing Dongfang Biotech Co., Ltd. | Exenatide | Phase 1 | Completed | 28 | 2023-10-19 |
| A Phase I Study of LY3502970 in Healthy ParticipantsNCT06085482 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 10 | 2023-10-19 |
| Semaglutide Therapy for Alcohol Reduction (STAR)NCT06015893 · National Institute on Drug Abuse (NIDA) | Semaglutide | Phase 2 | Recruiting | 80 | 2023-10-17 |
| A Study of Tirzepatide (LY3298176) Once Weekly in Adolescent Participants Who Have Obesity or Overweight With Weight-Related ComorbiditiesNCT06075667 · Eli Lilly and Company | Tirzepatide | Phase 3 | Active not recruiting | 160 | 2023-10-16 |
| Therapeutic Strategies for Microvascular Dysfunction in Type 1 DiabetesNCT05478707 · University of Virginia | Dulaglutide | Phase 2 | Suspended | 47 | 2023-10-05 |
| A Long-term Safety Study of Orforglipron (LY3502970) in Participants With Type 2 DiabetesNCT06010004 · Eli Lilly and Company | Orforglipron | Phase 3 | Completed | 401 | 2023-09-28 |
| A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 InhibitorNCT06065540 · Novo Nordisk A/S | SemaglutideCagrilintide | Phase 3 | Completed | 2734 | 2023-09-27 |
| A Study of Orforglipron (LY3502970) Compared With Semaglutide in Participants With Type 2 Diabetes Inadequately Controlled With MetforminNCT06045221 · Eli Lilly and Company | Orforglipron | Phase 3 | Completed | 1698 | 2023-09-22 |
| Clinical, Morphometric and Biochemical Effects on Adiposopathy Associated With the Use of GLP-1RA in CKDNCT07309094 · Cardenal Herrera University | LiraglutideDulaglutideExenatide | — | Recruiting | 250 | 2023-09-15 |
| Semaglutide for the Treatment of Glucose Intolerance in Women With Prior Gestational DiabetesNCT05569772 · Universitaire Ziekenhuizen KU Leuven | Semaglutide | Phase 3 | Recruiting | 252 | 2023-09-14 |
| A Study of LY3437943 in Postmenopausal Female Participants Who Are Overweight or ObeseNCT06039826 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 46 | 2023-09-12 |
| Research on Timing of Liraglutide Therapy in Patients With Obesity After Metabolic SurgeryNCT07374445 · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | Liraglutide | Phase 4 | Completed | 100 | 2023-09-01 |
| A Research Study Looking at Similarity Between LY3437943 Versions for Different Injection DevicesNCT06003465 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 57 | 2023-08-29 |
| A Research Study to See How Well CagriSema Helps People in China With Excess Body Weight Lose WeightNCT05996848 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Completed | 300 | 2023-08-15 |
| A Study of Orforglipron (LY3502970) in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise AloneNCT05971940 · Eli Lilly and Company | Orforglipron | Phase 3 | Completed | 559 | 2023-08-09 |
| A Trial to Evaluate Safety, Feasibility and Efficacy of the ReCET Procedure (EMINENT-2)NCT05984238 · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | Semaglutide | — | Completed | 33 | 2023-08-03 |
| A Study of Retatrutide (LY3437943) Once Weekly in Participants Who Have Obesity or Overweight and Osteoarthritis of the KneeNCT05931367 · Eli Lilly and Company | Retatrutide | Phase 3 | Completed | 445 | 2023-08-01 |
| A Study of Retatrutide (LY3437943) on Renal Function in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 DiabetesNCT05936151 · Eli Lilly and Company | Retatrutide | Phase 2 | Completed | 146 | 2023-07-20 |
| A Study of LY3437943 in Healthy Participants With a High Body Mass IndexNCT05959096 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 85 | 2023-07-18 |
| A Study of LY3437943 in Participants With Impaired and Normal Liver FunctionNCT05916560 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 43 | 2023-07-13 |
| A Phase 1, Parallel, Single-Dose, Open-Label, Single-Period Study of LY3502970 in Participants With Normal Renal Function and Participants With Renal Impairment.NCT05936138 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 24 | 2023-07-13 |
| A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or OverweightNCT05929079 · Eli Lilly and Company | Retatrutide | Phase 3 | Active not recruiting | 1000 | 2023-07-11 |
| A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or OverweightNCT05929066 · Eli Lilly and Company | Retatrutide | Phase 3 | Completed | 2335 | 2023-07-10 |
| Cathelicidin LL-37 Relation to Potentially Malignant LesionsNCT06219330 · Fayoum University | LL-37 | — | Completed | 45 | 2023-07-01 |
| Preoperative Weight Loss for Open Abdominal Wall ReconstructionNCT05925959 · Benjamin T. Miller | Liraglutide | — | Recruiting | 258 | 2023-06-19 |
| A Study of LY3502970 in Participants With Impaired and Normal Liver FunctionNCT05882032 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 29 | 2023-06-13 |
| A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight With Weight-Related ComorbiditiesNCT05869903 · Eli Lilly and Company | Orforglipron | Phase 3 | Active not recruiting | 3127 | 2023-06-05 |
| A Study of Orforglipron in Adult Participants With Obesity or Overweight and Type 2 DiabetesNCT05872620 · Eli Lilly and Company | Orforglipron | Phase 3 | Completed | 1613 | 2023-06-05 |
| A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular DiseaseNCT05882045 · Eli Lilly and Company | Retatrutide | Phase 3 | Active not recruiting | 1946 | 2023-05-30 |
| Effects of GH and Lirglutide on AgRPNCT05681299 · Columbia University | Liraglutide | Phase 4 | Recruiting | 40 | 2023-05-01 |
| Comparing the Efficacy of tDCS and tRNS to Improve Reading Skills in Children and Adolescents With DyslexiaNCT05832060 · Bambino Gesù Hospital and Research Institute | Selank | — | Unknown | 24 | 2023-05-01 |
| A Multiple Dose Study of LY3502970 in Healthy Overweight and Obese ParticipantsNCT05841238 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 52 | 2023-04-26 |
| Exenatide Pharmacokinetics and Pharmacodynamics in Gestational DiabetesNCT05482789 · Maisa N. Feghali, MD | Exenatide | Phase 4 | Recruiting | 13 | 2023-04-12 |
| Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2NCT05555589 · ReGenTree, LLC | Thymosin Beta-4 | Phase 3 | Recruiting | 70 | 2023-04-11 |
| A Research Study Looking at How a Single Dose of the Medicine Cagrilintide Works in Participants With Reduced Liver Function and in Healthy Participants With Normal Liver Function and How Cagrilintide is Absorbed and Used by the BodyNCT05564104 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Completed | 32 | 2023-04-05 |
| A Research Study to See How Well CagriSema Helps People in East Asia With Excess Body Weight Lose WeightNCT05813925 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Completed | 331 | 2023-04-03 |
| A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular RiskNCT05803421 · Eli Lilly and Company | Orforglipron | Phase 3 | Completed | 2749 | 2023-04-03 |
| REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood VesselsNCT05669755 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Active not recruiting | 7101 | 2023-03-01 |
| Clinical Study of 18F-Exendin-4 in InsulinomaNCT07340437 · Sichuan Provincial People's Hospital | Exenatide | — | Completed | 20 | 2023-02-01 |
| A Research Study to See How Well CagriSema Helps People With Type 2 Diabetes and Excess Body Weight Lose WeightNCT05394519 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Completed | 1200 | 2023-02-01 |
| A Research Study Comparing Wegovy to Other Weight Management Drugs in People Living With Obesity in AmericaNCT05579249 · Novo Nordisk A/S | Liraglutide | Phase 4 | Completed | 500 | 2023-01-19 |
| A Phase 3 Study to Evaluate the Efficacy of XW003 Compared With Dulaglutide in Participants With T2DMNCT05680129 · Hangzhou Sciwind Biosciences Co., Ltd. | Dulaglutide | Phase 3 | Completed | 623 | 2023-01-10 |
| A Study of Dulaglutide (LY2189265) in Participants With Type 2 Diabetes Mellitus in IndiaNCT05659537 · Eli Lilly and Company | Dulaglutide | Phase 4 | Completed | 212 | 2022-12-29 |
| Exenatide for Smoking Cessation and Prevention of Weight GainNCT05610800 · The University of Texas Health Science Center, Houston | Exenatide | Phase 2 | Completed | 140 | 2022-12-07 |
| A Study of Tirzepatide (LY3298176) in Adult Participants With Type 2 Diabetes Switching From Dulaglutide (SURPASS-SWITCH)NCT05564039 · Eli Lilly and Company | Dulaglutide | Phase 4 | Completed | 282 | 2022-11-30 |
| Effects of Glucagon-like-Peptide-1 Analogues on SexualityNCT05598008 · University Hospital, Basel, Switzerland | Liraglutide | — | Completed | 85 | 2022-11-25 |
| A Trial to Determine the Efficacy and Safety of Presendin in IIHNCT05347147 · Invex Therapeutics Ltd. | Exenatide | Phase 3 | Terminated | 14 | 2022-11-18 |
| Safety and Efficacy of Bimagrumab and Semaglutide in Adults Who Are Overweight or ObeseNCT05616013 · Eli Lilly and Company | Semaglutide | Phase 2 | Completed | 507 | 2022-11-16 |
| A Study of LY3437943 in Healthy Participants and Participants With Impaired Renal FunctionNCT05611957 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 29 | 2022-11-16 |
| A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose WeightNCT05567796 · Novo Nordisk A/S | Cagrilintide | Phase 3 | Active not recruiting | 3400 | 2022-11-01 |
| A Study of LY3437943 in Chinese Participants With Obesity Or OverweightNCT05548231 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 32 | 2022-10-24 |
| A Drug Interaction Study of Cyclosporine and LY3502970 in Healthy ParticipantsNCT05573230 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 32 | 2022-10-17 |
| LIGHT-MCI Trial: GLP-1 Agonist, SGLT2 Inhibitor, and DPP-4 Inhibitor for MCI Remission in Type 2 DiabetesNCT05313529 · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | Liraglutide | — | Active not recruiting | 396 | 2022-10-08 |
| PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 DiabetesNCT05390892 · Brigham and Women's Hospital | LiraglutideDulaglutide | Phase 4 | Recruiting | 6000 | 2022-09-26 |
| Cardiac and Metabolic Effects of Semaglutide in Heart Failure With Preserved Ejection FractionNCT05371496 · Mayo Clinic | Semaglutide | Phase 4 | Enrolling by invitation | 81 | 2022-09-06 |
| The Impact of Ibutamoren on Nonalcoholic Fatty Liver DiseaseNCT05364684 · Massachusetts General Hospital | MK-677 | Phase 2 | Completed | 12 | 2022-08-10 |
| A Drug Interaction Study of Clarithromycin and LY3502970 in Healthy ParticipantsNCT05469126 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 26 | 2022-08-01 |
| Efficacy and Safety Study of Thymosin Beta 4 in Patients With Acute Myocardial InfarctionNCT05984134 · Beijing Northland Biotech. Co., Ltd. | Thymosin Beta-4 | Phase 2 | Completed | 90 | 2022-07-15 |
| A Drug-Drug Interaction (DDI) Study of LY3437943 in Obese ParticipantsNCT05445232 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 32 | 2022-07-08 |
| Young Adults With Early-onset Obesity Treated With SemaglutideNCT05574439 · Signe Torekov | Semaglutide | Phase 4 | Completed | 246 | 2022-05-30 |
| A Study of LY3502970 in Healthy Overweight and Obese ParticipantsNCT05313802 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 72 | 2022-05-26 |
| GLP-1 Analogue in Preventing Progression of Small Vessel Disease (GAPP-SVD)NCT05356104 · Chinese University of Hong Kong | Exenatide | Phase 2 | Recruiting | 110 | 2022-05-25 |
| A Study of Two Different Formulations of LY3502970 in Healthy ParticipantsNCT05341089 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 39 | 2022-05-17 |
| Lifestyle Counseling and Medication for Adolescent Weight ManagementNCT04873245 · University of Minnesota | Semaglutide | Phase 2 | Completed | 120 | 2022-03-15 |
| Effects of GLP1-RA on Ectopic Fat Deposition in Chronic Kidney DiseaseNCT05254418 · Vanderbilt University Medical Center | Dulaglutide | Phase 2 | Completed | 7 | 2022-03-15 |
| Assessment of Pancreatic Beta Cell Mass and Function by Positron Emission Tomography Imaging in Human Diabetes MellitusNCT05662189 · Azienda Ospedaliero-Universitaria di Parma | Exenatide | — | Recruiting | 70 | 2022-03-15 |
| Adiponectin in Patients With Metabolic DisordersNCT07539584 · Moscow Regional Research and Clinical Institute (MONIKI) | Liraglutide | — | Completed | 130 | 2022-03-01 |
| Effect of Glucagon and Glucagon-like Peptide-1 Co-agonism on Cardiac Function and Metabolism in Overweight Participants with Type 2 DiabetesNCT04307797 · Cambridge University Hospitals NHS Foundation Trust | Exenatide | Phase 4 | Completed | 10 | 2022-01-18 |
| A Multiple-Dose Study of LY3502970 in Healthy ParticipantsNCT05110794 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 34 | 2021-11-05 |
| A Multiple Dose Study of LY3502970 in Healthy ParticipantsNCT05051566 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 26 | 2021-09-16 |
| Identification and Clinical Relevance of an Oxytocin Deficient State (GLP1 Study)NCT04897802 · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | Exenatide | Phase 4 | Completed | 42 | 2021-09-13 |
| Research Study to Look at How Well Cagrilintide Together With Semaglutide Works in People With Type 2 DiabetesNCT04982575 · Novo Nordisk A/S | Cagrilintide | Phase 2 | Completed | 92 | 2021-08-02 |
| Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes StudyNCT05220917 · Brigham and Women's Hospital | LiraglutideDulaglutideExenatide | — | Active not recruiting | 781430 | 2021-08-01 |
| GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose IntoleranceNCT04731272 · University of Pennsylvania | Dulaglutide | Phase 2 | Recruiting | 30 | 2021-07-16 |
| A Research Study to Compare Blood Levels of Cagrilintide and Semaglutide After Combined Versus Separate Injections in People With Overweight or ObesityNCT04940078 · Novo Nordisk A/S | Cagrilintide | Phase 1 | Completed | 40 | 2021-07-07 |
| Comparison of Type 2 Diabetes Pharmacotherapy RegimensNCT05073692 · Kaiser Permanente | Exenatide | — | Completed | 241981 | 2021-07-01 |
| Regulatory Post Marketing Surveillance (rPMS) Study of Xultophy® (Insulin Degludec/Liraglutide) to Evaluate Safety and Effectiveness in Patients With Type 2 Diabetes Mellitus in Routine Clinical Practice in KoreaNCT04952779 · Novo Nordisk A/S | Liraglutide | — | Completed | 750 | 2021-06-02 |
| A Study of LY3437943 in Japanese Participants With Type 2 Diabetes Mellitus (T2DM)NCT04823208 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 64 | 2021-05-24 |
| A Study of LY3437943 in Participants Who Have Obesity or Are OverweightNCT04881760 · Eli Lilly and Company | Retatrutide | Phase 2 | Completed | 338 | 2021-05-20 |
| A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE)NCT04777396 · Novo Nordisk A/S | Semaglutide | Phase 3 | Completed | 1840 | 2021-05-18 |
| A Study of LY3437943 in Participants With Type 2 DiabetesNCT04867785 · Eli Lilly and Company | Retatrutide | Phase 2 | Completed | 281 | 2021-05-13 |
| Exenatide-test for Diagnosing Endogenous Hyperinsulinemic HypoglycemiaNCT04909333 · University Hospital, Basel, Switzerland | Exenatide | — | Completed | 29 | 2021-04-29 |
| Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)NCT04822181 · Novo Nordisk A/S | Semaglutide | Phase 3 | Active not recruiting | 1205 | 2021-04-01 |
| Peri-implant Vitamin D and Cathelicidin (LL-37) LevelsNCT06867250 · Altinbas University | LL-37 | — | Completed | 33 | 2021-04-01 |
| Combined Active Treatment in Type 2 Diabetes With NASHNCT04639414 · German Diabetes Center | Semaglutide | Phase 4 | Completed | 192 | 2021-03-26 |
| SCALE KIDS: Research Study to Look at How Well a New Medicine is at Lowering Weight in Children With ObesityNCT04775082 · Novo Nordisk A/S | Liraglutide | Phase 3 | Active not recruiting | 78 | 2021-03-04 |
| Cathelicidin LL-37 Levels in the GCF and the Saliva of Smokers and Non-smokers With Stage III,IV PeriodontitisNCT04861493 · Cairo University | LL-37 | — | Completed | 60 | 2021-02-23 |
| Brain Activation and Satiety in Children 2NCT04520490 · Seattle Children's Hospital | Exenatide | Phase 3 | Active not recruiting | 63 | 2021-01-28 |
| Safety and Efficacy Study of Thymosin Beta 4 in Patients With Acute Myocardial Infarction.InfarctionNCT05485818 · Beijing Northland Biotech. Co., Ltd. | Thymosin Beta-4 | Phase 2 | Completed | 62 | 2020-11-23 |
| Effects of Exercise and GLP-1 Agonism on Muscle Microvascular Perfusion and Insulin Action in Adults With Metabolic SyndromeNCT04575844 · University of Virginia | Liraglutide | Phase 4 | Recruiting | 80 | 2020-11-01 |
| A Study of LY3502970 in Participants With Type 2 DiabetesNCT04426474 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 68 | 2020-10-08 |
| Exenatide Once-weekly as a Treatment for Multiple System AtrophyNCT04431713 · University College, London | Exenatide | Phase 2 | Completed | 50 | 2020-09-16 |
| A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 DiabetesNCT04255433 · Eli Lilly and Company | TirzepatideDulaglutide | Phase 3 | Completed | 13299 | 2020-05-29 |
| A Clinical Study of NLY01 in Patient's With Early Parkinson's DiseaseNCT04154072 · Neuraly, Inc. | Exenatide | Phase 2 | Completed | 255 | 2020-02-27 |
| Exenatide Once Weekly Over 2 Years as a Potential Disease Modifying Treatment for Parkinson's DiseaseNCT04232969 · University College, London | Exenatide | Phase 3 | Completed | 194 | 2020-01-20 |
| A Study of LY3437943 in Participants With Type 2 Diabetes Mellitus (T2DM)NCT04143802 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 72 | 2019-12-18 |
| Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)NCT03884075 · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Semaglutide | Phase 2 | Recruiting | 104 | 2019-07-24 |
| A Study of the Safety and Efficacy of Injectable Thymosin Beta 4 for Treating Acute Myocardial InfarctionNCT01311518 · RegeneRx Biopharmaceuticals, Inc. | Thymosin Beta-4 | Phase 2 | Withdrawn | 0 | 2019-07 |
| A Study of LY3502970 in Healthy ParticipantsNCT03929744 · Eli Lilly and Company | Orforglipron | Phase 1 | Completed | 133 | 2019-06-12 |
| Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-3NCT03937882 · ReGenTree, LLC | Thymosin Beta-4 | Phase 3 | Completed | 700 | 2019-05-24 |
| Imaging Pituitary ActiVation by ExendinNCT03923114 · Radboud University Medical Center | Exenatide | — | Completed | 20 | 2019-05-23 |
| Liraglutide Effect in Atrial FibrillationNCT03856632 · University of Miami | Liraglutide | Phase 4 | Active not recruiting | 60 | 2019-03-18 |
| A Safety Study of LY3437943 Given as a Single Injection in Healthy ParticipantsNCT03841630 · Eli Lilly and Company | Retatrutide | Phase 1 | Completed | 45 | 2019-03-13 |
| Glucagon-like Peptide-1 Receptor PET/CT in GLP-1R Related DiseaseNCT06725693 · Tianjin Medical University | Exenatide | — | Recruiting | 500 | 2019-02-01 |
| Growth Hormone Dynamics and Cardiac Steatosis in HIVNCT03826160 · Massachusetts General Hospital | Tesamorelin | — | Completed | 23 | 2019-01-30 |
| Growth Hormone Releasing Hormone Analog to Improve Nonalcoholic Fatty Liver Disease and Associated Cardiovascular RiskNCT03375788 · Massachusetts General Hospital | SermorelinTesamorelin | Phase 2 | Completed | 51 | 2019-01-17 |
| A Phase 1b Study of Thymosin Beta 4 in Healthy VolunteersNCT04555850 · Beijing Northland Biotech. Co., Ltd. | Thymosin Beta-4 | Phase 1 | Completed | 30 | 2018-07-30 |
| Tesamorelin to Improve Functional Outcomes After Peripheral Nerve InjuryNCT03150511 · Johns Hopkins University | Tesamorelin | Phase 2 | Recruiting | 36 | 2018-06-01 |
| Effects of GLP-1 Agonists on CArdiac Steatosis Evaluated by Magnetic Resonance ImagingNCT03498001 · Centre Hospitalier Universitaire Dijon | LiraglutideDulaglutide | — | Completed | 42 | 2018-04-16 |
| A Study for Comparison of Canagliflozin Versus Alternative Antihyperglycemic Treatments on Risk of Heart Failure Hospitalization and Amputation for Participants With Type 2 Diabetes Mellitus and the Subpopulation With Established Cardiovascular DiseaseNCT03492580 · Janssen Research & Development, LLC | DulaglutideExenatide | — | Completed | 714582 | 2018-02-22 |
| Body Composition and Adipose Tissue in HIVNCT03226821 · Columbia University | Tesamorelin | Phase 4 | Terminated | 6 | 2018-02-07 |
| The Cardiovascular Effect of GLP-1 Agonist, SGLT2 Inhibitor and Their CombinationNCT03878706 · University of Athens | LiraglutideMOTS-c | — | Recruiting | 240 | 2017-11-03 |
| The Effect of Growth Hormone Releasing Hormone on Cognitive Function in Individuals With Mild Cognitive ImpairmentNCT02553603 · The University of Texas Medical Branch, Galveston | SermorelinTesamorelin | Phase 1 | Completed | 22 | 2017-07-18 |
| A Phase 1a Study of Thymosin Beta 4 in Healthy VolunteersNCT04555824 · Beijing Northland Biotech. Co., Ltd. | Thymosin Beta-4 | Phase 1 | Completed | 54 | 2017-07-17 |
| Phase II Trial of Tesamorelin for Cognition in Aging HIV-Infected PersonsNCT02572323 · University of California, San Diego | Tesamorelin | Phase 2 | Completed | 73 | 2017-02-15 |
| Efficacy and Safety of Exenatide in the Treatment of Hypothalamic Obesity After Craniopharyngioma TherapyNCT02860923 · University Hospital, Bordeaux | Exenatide | Phase 3 | Completed | 42 | 2017-01-11 |
| Study of Intranasal Octreotide (DP1038) in Healthy Adult VolunteersNCT03031535 · Dauntless Pharmaceuticals | Sermorelin | Phase 1 | Completed | 32 | 2017-01 |
| Saxenda: Underlying Mechanisms and Clinical OutcomesNCT02944500 · Beth Israel Deaconess Medical Center | Liraglutide | Phase 4 | Active not recruiting | 28 | 2016-11 |
| Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome : ARISE-2NCT02974907 · ReGenTree, LLC | Thymosin Beta-4 | Phase 3 | Completed | 601 | 2016-11 |
| Impact of GHRH on Sleep Promotion and Endocrine Regulation in Service Members Who Sustained a Traumatic Brain Injury and Have Current InsomniaNCT02931474 · National Institute of Nursing Research (NINR) | Tesamorelin | Phase 2 | Withdrawn | 0 | 2016-10-06 |
| Evaluation of the Inhibitory Effects of Topical Ivermectin on Markers of Rosacea Specific Inflammation.NCT02806414 · University of California, San Diego | LL-37 | Phase 1/Phase 2 | Completed | 25 | 2016-07 |
| Pharmacogenomics of GLP1 Receptor AgonistsNCT05762744 · University of Maryland, Baltimore | Exenatide | Phase 1 | Terminated | 63 | 2016-06-01 |
| Dehydroepiandrosterone Versus Growth Hormone in Women Undergoing ICSI With Expected Poor Ovarian ResponseNCT02736591 · Cairo University | Sermorelin | Phase 3 | Unknown | 210 | 2016-06 |
| Timely Detection of Treatment Emergent Serious and Non-serious Adverse Events for Saxenda® in Mexican PatientsNCT02773355 · Novo Nordisk A/S | Liraglutide | — | Completed | 27 | 2016-05-16 |
| GLP-1 and Hyperoxia for Organ Protection in Heart SurgeryNCT02673931 · Rigshospitalet, Denmark | Exenatide | — | Active not recruiting | 1400 | 2016-02 |
| Therapeutic Benefit of Preoperative Supplemental Vitamin D in Patients Undergoing Major Surgical Procedures.NCT02138591 · University of Missouri, Kansas City | LL-37 | Phase 3 | Withdrawn | 0 | 2016-02 |
| Cohort Of DEafness-gene ScreeningNCT06133946 · Affiliated Hospital of Nantong University | MOTS-c | — | Active not recruiting | 35920 | 2016-01-01 |
| Extended Release Exenatide Versus Placebo In Diabetic Patients With Type 4 Cardiorenal SyndromeNCT02251431 · Baylor Research Institute | Exenatide | Phase 3 | Completed | 57 | 2015-11 |
| PCO-02 - Safety and Pharmacokinetics TrialNCT02637284 · PharmaCotherapia d.o.o. | BPC-157 | Phase 1 | Unknown | 42 | 2015-10 |
| Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-1NCT02597803 · ReGenTree, LLC | Thymosin Beta-4 | Phase 2/Phase 3 | Completed | 317 | 2015-09 |
| Tesamorelin Effects on Liver Fat and Histology in HIVNCT02196831 · Massachusetts General Hospital | SermorelinTesamorelin | — | Completed | 61 | 2015-07-01 |
| Estradiol-Receptor Blockade in Older Men and WomenNCT02271282 · Mayo Clinic | Sermorelin | Phase 1 | Completed | 40 | 2014-12 |
| Liver and Fat Regulation in Overweight Adolescent GirlsNCT02157974 · University of Colorado, Denver | Exenatide | Phase 2/Phase 3 | Completed | 92 | 2014-08 |
| Effect of Victoza on Dietary Preferences and Habit in Patients With Type 2 DiabetesNCT02674893 · Centre Hospitalier Universitaire Dijon | Liraglutide | Phase 4 | Terminated | 48 | 2014-02-04 |
| Platelet Reactivity, B-amyloid, MOTS-c and Mortality of Type II Diabetics With CADNCT04027712 · University of Athens | MOTS-c | — | Unknown | 120 | 2014-01-01 |
| Observational Longitudinal Study in Children Affected by Idiopathic Growth Hormone Deficiency (GHD)NCT02507245 · Stefania La Grutta, MD | Sermorelin | — | Completed | 48 | 2014-01 |
| Abdominal Obesity, Cardiovascular Inflammation, and Effects of Growth Hormone Releasing Hormone AnalogueNCT01632592 · Massachusetts General Hospital | SermorelinTesamorelin | — | Withdrawn | 0 | 2014-01 |
| A Comparative Effectiveness Study of Major Glycemia-lowering Medications for Treatment of Type 2 DiabetesNCT01794143 · GRADE Study Group | Liraglutide | Phase 3 | Completed | 7850 | 2013-05 |
| Long-term Observational Study in HIV Subjects Exposed to EGRIFTA®NCT01579695 · Theratechnologies | Tesamorelin | — | Terminated | 391 | 2013-02 |
| Effects of Transcranial Magnetic Stimulation on Object RecognitionNCT01747200 · National Institute of Neurological Disorders and Stroke (NINDS) | Selank | — | Completed | 13 | 2012-11-16 |
| Effect of Liraglutide on Fatty Liver Content and Lipoprotein MetabolismNCT02721888 · Centre Hospitalier Universitaire Dijon | Liraglutide | Phase 4 | Terminated | 127 | 2012-07-10 |
| Diabetic Retinopathy in HIV Subjects Treated With EGRIFTA®NCT01591902 · Theratechnologies | Tesamorelin | Phase 4 | Terminated | 129 | 2012-06 |
| Egrifta Replacement and Sleep Disordered BreathingNCT01788462 · Johns Hopkins University | Tesamorelin | — | Withdrawn | 0 | 2012-05 |
| Effects of Smoking and Vitamin D3 on the Levels of Human Cathelicidin Peptide LL-37NCT03923218 · Gazi University | LL-37 | — | Completed | 60 | 2011-12 |
| Efficacy and Safety Study of Tesamorelin in Chronic Obstructive Pulmonary Disease (COPD) Subjects With Muscle WastingNCT01388920 · Theratechnologies | Tesamorelin | Phase 2 | Terminated | 3 | 2011-09 |
| Safety and Efficacy of Thymosin Beta 4 Ophthalmic Solution in Patients With Dry EyeNCT01387347 · ReGenTree, LLC | Thymosin Beta-4 | Phase 2 | Completed | 72 | 2011-08 |
| Effects of Aminocaproic Acid (ACA) on Rosacea-specific InflammationNCT01398280 · University of California, San Diego | LL-37 | EARLY_Phase 1 | Completed | 15 | 2011-07 |
| Vitamin D in Ventilated ICU PatientsNCT01372995 · Emory University | LL-37 | Phase 2 | Completed | 31 | 2011-07 |
| Three Month Treatment of Growth Hormone Releasing Hormone (GHRH) in the ElderlyNCT01410799 · University of Pennsylvania | Sermorelin | Phase 2 | Terminated | 13 | 2011-05 |
| Safety and Efficacy of Ipamorelin Compared to Placebo for the Recovery of Gastrointestinal FunctionNCT01280344 · Helsinn Therapeutics (U.S.), Inc | Ipamorelin | Phase 2 | Completed | 320 | 2011-04 |
| Comparative Study of Thymosin Beta 4 Eye Drops vs. Vehicle in the Treatment of Severe Dry EyeNCT01393132 · Michigan Cornea Consultants, PC | Thymosin Beta-4 | Phase 2 | Completed | 9 | 2011-03 |
| VRS-317 in Adult Subjects With Growth Hormone DeficiencyNCT01359488 · Versartis Inc. | Sermorelin | Phase 1 | Completed | 50 | 2011-03 |
| Effect of GLP-1 Receptor (GLP-1R) Agonists on Cardiac Function and on Epicardial Adipose Tissue (EAT) Volume and on Myocardial TG Content in Obese DiabeticsNCT02042664 · Assistance Publique Hopitaux De Marseille | Exenatide | Phase 3 | Completed | 44 | 2011-01 |
| Effects of Growth Hormone Releasing Hormone in HIVNCT01263717 · Massachusetts General Hospital | SermorelinTesamorelin | — | Completed | 54 | 2010-12 |
| Growth Hormone Secretagogue MK-0677's Effect on Lean Body Mass in Chronic Kidney Disease Stage 4/5 SubjectsNCT01343641 · University of Virginia | MK-677 | Phase 2 | Withdrawn | 0 | 2009-03 |
| Effects of Short-term Growth Hormone in HIV-infected PatientsNCT00795210 · Massachusetts General Hospital | SermorelinTesamorelin | — | Completed | 25 | 2009-02 |
| Effect of Short Term Growth Hormone Releasing Hormone in Healthy MenNCT00850564 · Massachusetts General Hospital | SermorelinTesamorelin | — | Completed | 15 | 2009-02 |
| Durability of Combination Therapy With Exenatide/Pioglitazone/Metformin vs. Conventional Therapy in New Onset T2DMNCT01107717 · The University of Texas Health Science Center at San Antonio | Exenatide | Phase 4 | Completed | 318 | 2009-01 |
| Vitamin D in Active Tuberculosis (TB) StudyNCT00788320 · Atlanta VA Medical Center | LL-37 | — | Withdrawn | 0 | 2008-10 |
| Effectiveness of Growth Hormone Releasing Hormone in Reducing Abdominal Fat in People Who Are ObeseNCT00675506 · Massachusetts General Hospital | SermorelinTesamorelin | Phase 2 | Completed | 60 | 2008-07 |
| Pharmacokinetic and Pharmacodynamic Study of TH9507, a Growth Hormone-Releasing Factor Analog, in HIV Positive PatientsNCT02012556 · Theratechnologies | SermorelinTesamorelin | Phase 1 | Completed | 18 | 2008-05 |
| A Phase 1 Safety Study of the Intravenous Administration of Thymosin Beta in Healthy VolunteersNCT00743769 · RegeneRx Biopharmaceuticals, Inc. | Thymosin Beta-4 | Phase 1 | Withdrawn | 0 | 2008-04 |
| Safety and Efficacy of Ipamorelin for Management of Post-Operative IleusNCT00672074 · Helsinn Therapeutics (U.S.), Inc | Ipamorelin | Phase 2 | Completed | 117 | 2008-04 |
| Six Month Treatment of Growth Hormone Releasing Hormone (GHRH) in the ElderlyNCT00807365 · Johns Hopkins University | Sermorelin | Phase 2 | Terminated | 5 | 2007-12-17 |
| A Phase 2 Study of the Safety and Efficacy of Thymosin Beta 4 for Treating Corneal WoundsNCT00598871 · ReGenTree, LLC | Thymosin Beta-4 | Phase 2 | Terminated | 12 | 2007-12 |
| Islet Transplantation in Type 1 Diabetic Patients Using the University of Illinois at Chicago (UIC) ProtocolNCT00679042 · CellTrans Inc. | Exenatide | Phase 3 | Active not recruiting | 21 | 2007-09-05 |
| TH9507 Extension Study in Patients With HIV-Associated LipodystrophyNCT00608023 · Theratechnologies | SermorelinTesamorelin | Phase 3 | Completed | 263 | 2007-08 |
| Sexually Dimorphic Effects of GHRH in Adult Growth Hormone TestingNCT00324064 · Children's Mercy Hospital Kansas City | Sermorelin | — | Completed | 90 | 2007-07 |
| Adult Growth Hormone Deficiency and Cardiovascular RiskNCT00720902 · Columbia University | Sermorelin | Phase 4 | Terminated | 7 | 2007-02 |
| GLP-1 Receptor Agonists and Alzheimer's Disease: A Multi-National Target Trial EmulationNCT07677865 · West China Hospital | SemaglutideTirzepatideLiraglutide | — | Completed | 213891 | 2007-01-01 |
| Growth Hormone Secretagogue MK-0677 Effect on IGF-1 Levels in ESRD PatientsNCT00395291 · University of Virginia | MK-677 | — | Completed | 49 | 2006-08 |
| Study of Thymosin Beta 4 in Patients With Venous Stasis UlcersNCT00832091 · RegeneRx Biopharmaceuticals, Inc. | Thymosin Beta-4 | Phase 2 | Completed | 72 | 2006-07 |
| Study of Thymosin Beta 4 in Patients With Pressure UlcersNCT00382174 · RegeneRx Biopharmaceuticals, Inc. | Thymosin Beta-4 | Phase 2 | Completed | 72 | 2006-05 |
| A Phase 2 Study on Effect of Thymosin Beta 4 on Wound Healing in Patients With Epidermolysis BullosaNCT00311766 · RegeneRx Biopharmaceuticals, Inc. | Thymosin Beta-4 | Phase 2 | Terminated | 30 | 2006-02 |
| SMART: Somatotrophics, Memory, and Aging Research TrialNCT00257712 · University of Washington | SermorelinTesamorelin | Phase 2 | Completed | 151 | 2006-02 |
| A Study to Evaluate CJC 1295 in HIV Patients With Visceral ObesityNCT00267527 · ConjuChem | CJC-1295 | Phase 2 | Terminated | 120 | 2005-12 |
| Treatment of Sarcopenia in Post-Hip Fracture Patients (0677-032)NCT00128115 · Merck Sharp & Dohme LLC | MK-677 | Phase 2 | Terminated | 83 | 2005-09 |
| Efficacy and Safety of an Oral Growth Hormone Drug in the Treatment of FibromyalgiaNCT00116129 · Bennett, Robert, M.D. | MK-677 | Phase 2 | Completed | 64 | 2005-07 |
| TH9507 in Patients With HIV-Associated LipodystrophyNCT00123253 · Theratechnologies | SermorelinTesamorelin | Phase 3 | Completed | 412 | 2005-06 |
| The Effect of GHRH Therapy on Myocardial Structure and Function in Congestive Heart FailureNCT00791843 · University of Pennsylvania | Sermorelin | Phase 2 | Completed | 3 | 2004-03 |
| Comparative Validation of the Growth Hormone Releasing Hormone and Arginine Test for the Diagnosis of Adult Growth Hormone DeficiencyNCT01060488 · Merck KGaA, Darmstadt, Germany | Sermorelin | Phase 3 | Completed | 69 | 2004-01 |
| Study of MK0677 for the Treatment of Alzheimer's Disease (0677-030)(COMPLETED)NCT00074529 · Merck Sharp & Dohme LLC | MK-677 | Phase 2 | Completed | 512 | 2003-10 |
| Safety Study of TH9507 in Subjects With Stable, Type 2 DiabetesNCT01264497 · Theratechnologies | Tesamorelin | Phase 2 | Completed | 55 | 2002-02 |
| Diagnosing Adult Growth Hormone DeficiencyNCT03018886 · Helsinki University Central Hospital | Sermorelin | — | Completed | 160 | 2001-05 |
| Effects of an Oral GH Secretagogue (MK-677) on Body Composition and Functional Ability of Older AdultsNCT00474279 · University of Virginia | MK-677 | Phase 1/Phase 2 | Completed | 72 | 1998-07 |
| Growth Hormone Releasing Hormone (GHRH) Treatment for Age-Related Sleep DisturbancesNCT00000380 · University of Washington | Sermorelin | — | Completed | — | 1996-06 |
| Study of the Effect of Growth Hormone-Releasing Hormone Antagonist on Growth Hormone Release in AcromegalyNCT00004332 · National Center for Research Resources (NCRR) | Sermorelin | — | Completed | 148 | 1993-05 |
| Provide Pre-approval Expanded Access of LY3437943NCT07629401 · Eli Lilly and Company | Retatrutide | — | Available | — | — |