122 articles in GLP-1 & Metabolic · page 3 of 11

GLP-1 & Metabolic··9 min read

GLP-1 Cost: What You Actually Pay, and the Conditions Attached

Headline GLP-1 prices are conditional offers. The 45-day refill windows, new-patient limits, expiry dates, and annual caps are where the real cost lives.

Read →
GLP-1 & Metabolic··9 min read

GLP-1 Overdose: What the Reported Cases Actually Show

US poison centers logged 10,033 GLP-1 exposures from 2012 to 2023. Most were dosing errors with mild symptoms, but referrals to care rose sharply.

Read →
GLP-1 & Metabolic··9 min read

GLP-1 Pills: How Oral Semaglutide and Orforglipron Compare

Two GLP-1 pills are now FDA approved. Their headline numbers use different statistical estimands, which makes the obvious comparison misleading.

Read →
GLP-1 & Metabolic··8 min read

GLP-1 Supplements: Does Anything Actually Boost GLP-1?

Berberine is sold as nature's Ozempic. Pooled trials found no significant weight effect, and its mechanism is AMPK — not GLP-1 at all.

Read →
GLP-1 & Metabolic··7 min read

Missed a GLP-1 Dose? How to Get Back on Schedule

Missed a semaglutide or tirzepatide dose? The exact label rules (the 2-day, 5-day, and 4-day windows) for what to do and how to get back on schedule.

Read →
GLP-1 & Metabolic··9 min read

Peptides for Fat Loss: What the Evidence Shows

The peptides with real fat-loss evidence are the approved GLP-1 drugs. The ones marketed as fat-loss peptides are graded unknown or unsupported.

Read →
GLP-1 & Metabolic··7 min read

How Much GLP-1 Weight Loss Is Fat vs Muscle?

What the DEXA substudies of semaglutide and tirzepatide show about GLP-1 fat vs muscle loss — how much of the weight is lean mass, and how to protect it.

Read →
GLP-1 & Metabolic··7 min read

GLP-1 Weight Loss by Starting Weight: Why % Beats Pounds

Why GLP-1 weight loss is reported in percent, not pounds — how the same percentage becomes very different pounds, and what the trials show.

Read →
GLP-1 & Metabolic··9 min read

How to Measure Whether You're Actually Losing Muscle

DEXA, BIA, the scale, and a tape measure each say something different about muscle loss on a GLP-1. What each can and cannot actually reveal.

Read →
GLP-1 & Metabolic··8 min read

Is Your GLP-1 Weight Loss Normal? Benchmarking the Curve

Average monthly weight loss on Wegovy and Zepbound, straight from the trials — a benchmark for your own progress, and why the range is wide.

Read →
GLP-1 & Metabolic··7 min read

When Does GLP-1 Weight Loss Start? The First Month

What the trials show about GLP-1 weight-loss onset in the first month, why the starting dose is deliberately slow, and what is normal early.

Read →
GLP-1 & Metabolic··7 min read

Average Weight Loss on Zepbound: The SURMOUNT Numbers

What SURMOUNT-1 found for tirzepatide by dose: average percent loss at 5, 10, and 15 mg — and why an average is not a promise for anyone.

Read →