Longevity
Biomarkers, healthy aging, preventative health, and lifespan research.
103 articles in Longevity · page 5 of 9
Reading a Longevity Study: Mice Aren't Men
What the NIA Interventions Testing Program and the animal-to-human translation data show about how much a mouse lifespan result is actually worth.
Read →Frailty and Aging: Prevention Strategies
Frailty is partly preventable and sometimes reversible. What the trial evidence supports on exercise, protein, and multi-domain programs.
Read →Why Most Longevity Supplements Disappoint
The structural reasons the supplement aisle rarely matches the press releases: preclinical models, dose gaps, and endpoints that never move.
Read →The Longevity Escape Velocity Debate
Longevity escape velocity is a 2004 hypothesis, not a finding — and life-expectancy gains in the longest-lived countries have slowed since 1990.
Read →Purpose and Lifespan: The Psychological Evidence
Purpose in life tracks with lower mortality across large cohorts. What that observational finding can and cannot establish.
Read →Social Connection and Longevity
A 148-study meta-analysis tied stronger social ties to 50% higher odds of survival. Why the effect is large, and what the caveats are.
Read →VO2 Max and Lifespan: The Most Underrated Longevity Marker
In 122,007 patients, the least-fit faced ~5x the mortality of the fittest — with low fitness outranking smoking, diabetes, and coronary disease as a risk.
Read →Walking and Lifespan: The Steps That Matter
How much walking actually moves the mortality needle, why 10,000 steps was never the threshold, and where the benefit curve flattens out.
Read →Measuring Healthspan vs Lifespan
Years in good health may matter more than total years, but healthspan is genuinely hard to measure. How researchers try, and fail.
Read →The Longevity Diet: What the Evidence Supports
Cutting through the diet wars to the eating patterns that consistently track with longer, healthier life — and the ones that don't.
Read →Polyphenols and Aging: Beyond the Headlines
Polyphenol-rich diets track with lower mortality; trials of isolated polyphenols keep missing their primary endpoints. Where that gap comes from.
Read →Testosterone and Longevity in Men
Separating age-related decline, actual symptoms, and the trial evidence on intervention — what testosterone therapy has and has not shown.
Read →