GLP-1 & Metabolic
Metabolic health, appetite regulation, and modern weight management.
122 articles in GLP-1 & Metabolic · page 6 of 11
What Is Zepbound? A Plain-Language Explainer
Zepbound is Eli Lilly's weekly injectable for chronic weight management. What tirzepatide is, what the trials showed, and how it differs from Mounjaro.
Read →Does Ozempic Cause Hair Loss? What the Evidence Shows
Hair shedding on GLP-1s is real but usually indirect — a response to rapid weight loss rather than the drug itself. What the trials report and what helps.
Read →Mounjaro vs Zepbound: Same Drug, Different Label
Mounjaro and Zepbound are both tirzepatide from Eli Lilly. The difference is the approved indication, not the molecule inside the pen.
Read →Ozempic vs Wegovy: Same Drug, Different Label
Ozempic and Wegovy are both semaglutide made by the same company. What actually separates them is dose, approved use, and how they're paid for.
Read →Reading a GLP-1 Headline Without Getting Misled
Relative versus absolute risk, surrogate versus hard endpoints, and who got counted — reading GLP-1 headlines against the real trial numbers.
Read →GLP-1s and Bone Density: An Open Question
Rapid weight loss can affect bone. What the limited trial data shows on GLP-1s and bone density, and why it is worth watching.
Read →Semaglutide and Cardiovascular Risk: What SELECT Actually Showed
The SELECT trial found a 20% reduction in major cardiac events in people with heart disease and excess weight — and it changed the drug's FDA label.
Read →The Side-Effect Curve: Why Most Quit in Month One
What the pivotal trials and a real-world cohort show about GLP-1 side-effect timing and when people quit — the early-quit story is half right.
Read →GLP-1s for Maintenance vs Active Loss
In the STEP 1 extension, people regained two-thirds of lost weight a year after stopping semaglutide. Maintenance needs the drug.
Read →What 'Food Noise' Tells Us About Obesity Biology
A patient-coined phrase is reframing appetite as biology. What the brain-imaging evidence does and does not yet support.
Read →GLP-1s and Mental Health: Untangling the Signals
Regulators found no causal link to suicidal thoughts, but the data still cannot promise mood neutrality for every individual.
Read →Can Training Offset GLP-1 Muscle Loss?
Resistance training is the obvious lever against lean-mass loss. What the evidence says it can protect on a GLP-1, and what it cannot.
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