Titration
In plain language
Gradually increasing a medication dose over time to reach the target while limiting side effects.
Technical definition
The stepwise adjustment of a drug's dose according to a defined schedule or clinical response, used to balance efficacy against tolerability.
GLP-1 and dual agonists are almost always titrated, starting low and stepping up every few weeks, because a slower ramp reduces nausea and other gastrointestinal effects while the body adapts.